Ahmed Zunirah, Divatia Mukul K, Crumley Suzanne, Victor David W, Kodali Sudha
Division of Gastroenterology and Hepatology, Houston Methodist, Houston, TX.
Department of Pathology and Genomic Medicine, Houston Methodist, Houston, TX.
ACG Case Rep J. 2023 Jul 8;10(7):e00931. doi: 10.14309/crj.0000000000000931. eCollection 2023 Jul.
Neuroendocrine tumors originate from neuroendocrine cells primarily located in the gastrointestinal tract. These tumors often metastasize to the liver. Primary hepatic neuroendocrine carcinomas are uncommon, and combined hepatocellular neuroendocrine carcinomas are exceedingly rare. There is a lack of data on the management of these rare tumors. Most cases have very poor prognosis secondary to aggressive behavior of the neuroendocrine tumor component. It is important for clinicians to be aware of this rare carcinoma to allow for early diagnosis and optimize potential treatment options.
神经内分泌肿瘤起源于主要位于胃肠道的神经内分泌细胞。这些肿瘤常转移至肝脏。原发性肝神经内分泌癌并不常见，而肝细胞神经内分泌癌合并存在则极为罕见。关于这些罕见肿瘤的治疗缺乏相关数据。大多数病例由于神经内分泌肿瘤成分的侵袭性而预后很差。临床医生了解这种罕见癌症很重要，以便能早期诊断并优化潜在的治疗方案。
