Proskuriakova Ekaterina, Jasaraj Ranjit B, San Hernandez Aleyda M, Sakhuja Anuradha, Khoury Mtanis, Khosla Pam
Internal Medicine, Mount Sinai Hospital, Chicago, USA.
Hematology and Oncology, Mount Sinai Hospital, Chicago, USA.
Cureus. 2023 Jun 10;15(6):e40210. doi: 10.7759/cureus.40210. eCollection 2023 Jun.
Aplastic anemia (AA) is a severe but rare hematologic condition associated with hematopoietic failure leading to decreased or total absent hematopoietic precursor cells in the bone marrow. AA presents at any age with equal distribution among gender and race. There are three known mechanisms of AA: direct injuries, immune-mediated disease, and bone marrow failure. The most common etiology of AA is considered to be idiopathic. Patients usually present with non-specific findings, such as easy fatigability, dyspnea on exertion, pallor, and mucosal bleeding. The primary treatment of AA is to remove the offending agent. In patients in whom the reversible cause was not found, patient management depends on age, disease severity, and donor availability. Here, we present a case of a 35-year-old male who presented to the emergency room with profuse bleeding after a deep dental cleaning. He was found to have pancytopenia on his laboratory panel and had an excellent response to immunosuppressive therapy.
再生障碍性贫血（AA）是一种严重但罕见的血液系统疾病，与造血功能衰竭相关，导致骨髓中造血前体细胞减少或完全缺失。AA可发生于任何年龄，在性别和种族中分布均衡。已知AA有三种发病机制：直接损伤、免疫介导性疾病和骨髓衰竭。AA最常见的病因被认为是特发性的。患者通常表现为非特异性症状，如容易疲劳、活动后呼吸困难、面色苍白和黏膜出血。AA的主要治疗方法是去除致病因素。对于未发现可逆病因的患者，治疗方案取决于年龄、疾病严重程度和供体可用性。在此，我们报告一例35岁男性患者，在深度洗牙后出现大量出血，就诊于急诊室。实验室检查发现他全血细胞减少，对免疫抑制治疗反应良好。
