Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Department of Oncology, Affiliated Hospital of Jiangnan University, Wuxi, China.
J Psychosoc Oncol. 2024;42(2):175-189. doi: 10.1080/07347332.2023.2231431. Epub 2023 Jul 12.
To better understand the relationship between family functioning, resilience, and quality of life (including physical and mental component score, PCS and MCS) in patients with advanced colorectal cancer (CRC) to predict and improve their quality of life. A cross-sectional study was conducted in which a total of 165 patients with advanced colorectal cancer participated in a one-time survey. Measures included the Family Functioning Assessment Device, the 10-item Connor-Davidson Resilience Scale, and the SF-12 Health Survey Assessment Scale. The data analysis methods included descriptive analysis, pearson's correlation analysis, -tests, and nonparametric tests. Of the patients with advanced CRC, 47.27% and 72.73% had moderate or low mental and physical health components, respectively. The results indicated that in patients with advanced CRC, family function was negatively correlated with resilience ( < 0.01), family functioning was negatively correlated with MCS ( < 0.01), and resilience was positively correlated with PCS ( < 0.05) and MCS ( < 0.01). The mediating analysis revealed that family functioning regulated MCS through resilience (effect value = 13.17%). Our findings suggest that the MCS of patients with advanced CRC is influenced by both family functioning and resilience. PCS in patients with advanced CRC appears to be influenced by resilience but not by family functioning.
为了更好地理解晚期结直肠癌患者家庭功能、韧性和生活质量（包括生理和心理成分评分、PCS 和 MCS）之间的关系，以预测和改善他们的生活质量。本研究采用横断面研究方法，共纳入 165 例晚期结直肠癌患者进行一次性调查。研究工具包括家庭功能评估工具、Connor-Davidson 韧性量表的 10 项、SF-12 健康调查评估量表。数据分析方法包括描述性分析、Pearson 相关分析、t 检验和非参数检验。在晚期 CRC 患者中，47.27%和 72.73%的患者分别存在中度或低心理健康和生理健康成分。结果表明，在晚期 CRC 患者中，家庭功能与韧性呈负相关（<0.01），家庭功能与 MCS 呈负相关（<0.01），韧性与 PCS（<0.05）和 MCS（<0.01）呈正相关。中介分析显示，家庭功能通过韧性调节 MCS（效应值=13.17%）。本研究结果提示，晚期 CRC 患者的 MCS 同时受到家庭功能和韧性的影响，而 PCS 似乎仅受韧性影响，不受家庭功能影响。
