用芴甲氧羰基-二苯基丙氨酸设计一种无载体的抗菌局部水凝胶。
Designing a vehicle-free anti-bacterial topical hydrogel from Fmoc-diphenylalanine.
作者信息
Roy Nabanita, Datta Hemanta Kumar, Roy Rajdip, Dastidar Parthasarathi
机构信息
School of Chemical Sciences, Indian Association for the Cultivation of Science (IACS), 2A and 2B Raja S.C. Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India.
出版信息
Chem Commun (Camb). 2023 Jul 27;59(61):9400-9403. doi: 10.1039/d3cc01922e.
PMID:37435840
Abstract
A supramolecular synthon-based salt formation strategy has been employed to afford an anti-bacterial topical hydrogel from Fmoc-diphenylalanine (FmocFF). The nontrivial steps (pH/solvent switch along with heat-cool protocol) required for making the hydrogel from FmocFF were successfully avoided following this strategy.
摘要
一种基于超分子合成子的盐形成策略已被用于从芴甲氧羰基-二苯基丙氨酸（FmocFF）制备一种抗菌局部水凝胶。遵循该策略成功避免了由FmocFF制备水凝胶所需的复杂步骤（pH/溶剂切换以及加热-冷却方案）。
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