Center for Advanced Orthopedic Studies, Department of Orthopedic Surgery, Beth Israel Deaconess Medical Center, Boston, MA, United States.
Center for Advanced Orthopedic Studies, Department of Orthopedic Surgery, Beth Israel Deaconess Medical Center, Boston, MA, United States; Department of Orthopedic Surgery, Harvard Medical School, Boston, MA, United States.
J Biomech. 2023 Aug;157:111710. doi: 10.1016/j.jbiomech.2023.111710. Epub 2023 Jul 1.
Trunk muscle size and location relative to the spine are key factors affecting their capacity to assist in trunk movement, strength, and function. There remains limited information on how age, weight and height affect these measurements across multiple spinal levels, and prior studies had limited samples in terms of size and ethnicity. In this study, we measured trunk muscles in coronal plane slices at T4 - L4 of CT scans acquired in 507 participants, aged 40-90 years, from the community-based Framingham Heart Study. Mixed-effects linear regressions, stratified by sex, determined the contributions of age, height and weight, to muscle cross-sectional area (CSA), the distance from the vertebral body centroid (CD), and the in-plane angle of the line between the vertebral body and the muscle centroids (CA). Muscle CSA decreased with higher age by an average of -0.8% per year, but weight (average 0.8% per kg) and height (average -0.05% per cm) had mixed results, with both positive and negative effects depending on muscle group and level. Muscle CD increased with weight by an average of 0.3% per kg, but had mixed effects for age (average 0.8% per year) and height (average 0.1% per cm). Muscle CA had mixed associations with age (average 0.05% per year), weight (average 0.01% per kg) and height (average -0.05% per cm). A prediction program created with these results provides a simple approach for estimating probable values for trunk muscle size and position in the absence of medical imaging.
躯干肌肉的大小和位置与脊柱的关系是影响其协助躯干运动、力量和功能的关键因素。目前关于年龄、体重和身高如何影响这些测量值在多个脊柱水平上的信息有限，而且之前的研究在样本量和种族方面都存在局限性。在这项研究中，我们在社区为基础的弗雷明汉心脏研究（Framingham Heart Study）中，对 507 名年龄在 40 至 90 岁之间的参与者的 CT 扫描的 T4 - L4 冠状面切片进行了测量。混合效应线性回归，按性别分层，确定了年龄、身高和体重对肌肉横截面积（CSA）、椎体中心点（CD）的距离以及椎体和肌肉中心点之间的线的平面角（CA）的贡献。肌肉 CSA 随年龄的增加而平均每年减少 0.8%，但体重（平均每公斤增加 0.8%）和身高（平均每厘米减少 0.05%）的影响则各不相同，取决于肌肉群和水平，既有正效应，也有负效应。肌肉 CD 随体重的增加而平均增加 0.3%/kg，但与年龄（平均每年增加 0.8%）和身高（平均每厘米增加 0.1%）的影响则各不相同。肌肉 CA 与年龄（平均每年增加 0.05%）、体重（平均每公斤增加 0.01%）和身高（平均每厘米减少 0.05%）的关系也较为复杂。根据这些结果创建的预测程序为在没有医学影像的情况下估计躯干肌肉大小和位置的可能值提供了一种简单的方法。
