Tan Rachel, Baranauskas Marissa N, Karl Sean T, Ortiz de Zevallos Joaquin, Shei Ren-Jay, Paris Hunter L, Wiggins Chad C, Bailey Stephen J
Department of Sports Medicine, Pepperdine University, Malibu, CA, 90263, USA.
Department of Human Physiology & Nutrition, University of Colorado, Colorado Springs, CO, 80918, USA.
Nitric Oxide. 2023 Sep 1;138-139:105-119. doi: 10.1016/j.niox.2023.06.004. Epub 2023 Jul 10.
Increasing evidence indicates that dietary nitrate supplementation has the potential to increase muscular power output during skeletal muscle contractions. However, there is still a paucity of data characterizing the impact of different nitrate dosing regimens on nitric oxide bioavailability and its potential ergogenic effects across various population groups. This review discusses the potential influence of different dietary nitrate supplementation strategies on nitric oxide bioavailability and muscular peak power output in healthy adults, athletes, older adults and some clinical populations. Effect sizes were calculated for peak power output and absolute and/or relative nitrate doses were considered where applicable. There was no relationship between the effect sizes of peak power output change following nitrate supplementation and when nitrate dosage when considered in absolute or relative terms. Areas for further research are also recommended including a focus on nitrate dosing regimens that optimize nitric oxide bioavailability for enhancing peak power at times of increased muscular work in a variety of healthy and disease populations.
越来越多的证据表明，补充膳食硝酸盐有潜力在骨骼肌收缩期间提高肌肉力量输出。然而，关于不同硝酸盐给药方案对一氧化氮生物利用度的影响及其在不同人群中的潜在促运动效果的数据仍然匮乏。本综述讨论了不同膳食硝酸盐补充策略对健康成年人、运动员、老年人和一些临床人群中一氧化氮生物利用度和肌肉峰值功率输出的潜在影响。计算了峰值功率输出的效应大小，并在适用的情况下考虑了绝对和/或相对硝酸盐剂量。以绝对或相对方式考虑时，补充硝酸盐后峰值功率输出变化的效应大小与硝酸盐剂量之间没有关系。还建议了进一步研究的领域，包括关注能优化一氧化氮生物利用度的硝酸盐给药方案，以便在各种健康和疾病人群的肌肉工作量增加时增强峰值功率。
