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虹鳟(萨氏虹鳟)对二硝基苯-钥孔戚血蓝蛋白体液反应的变异性。正常虹鳟与通过雌核发育或自体受精获得的虹鳟之间抗体动力学和免疫球蛋白光谱类型的比较。

Variability in humoral responses to DNP-KLH of rainbow trout (Salmo gairdneri). Comparison of antibody kinetics and immunoglobulins spectrotypes between normal trouts and trouts obtained by gynogenesis or self-fertilization.

作者信息

Cossarini-Dunier M, Desvaux F X, Dorson M

出版信息

Dev Comp Immunol. 1986 Spring;10(2):207-17. doi: 10.1016/0145-305x(86)90004-2.

DOI:10.1016/0145-305x(86)90004-2
PMID:3743849
Abstract

The anti-DNP antibody responses were compared between conventional trouts produced in fishfarm and trouts experimentally obtained by self-fertilization of hermaphrodites or by gynogenesis. The variability of anti-DNP antibody titres was equivalent between normal and gynogenetic fish, but significantly reduced for fish obtained by self-fertilization. Isoelectrofocusing analysis of individually-isolated anti-DNP antibodies indicate low molecular heterogeneity but large variability between conventional trouts. Almost complete sharing of individual spectrotypes was observed between self-fertilized fish and large similarities between gynogenetics animals. These results suggest that the intensity of antibody synthesis in trout is under a complex genetic control, even in inbred animals expressing large similarities in their antibody repertoires.

摘要

对养殖场养殖的传统虹鳟鱼与通过雌雄同体自体受精或雌核发育实验获得的虹鳟鱼的抗二硝基苯酚(DNP)抗体反应进行了比较。正常鱼和雌核发育鱼的抗DNP抗体滴度变异性相当,但自体受精获得的鱼的变异性显著降低。对单独分离的抗DNP抗体进行等电聚焦分析表明,传统虹鳟鱼之间存在低分子异质性但变异性很大。在自体受精的鱼之间观察到几乎完全相同的个体光谱类型,在雌核发育动物之间也有很大的相似性。这些结果表明,即使在抗体库有很大相似性的近交动物中,虹鳟鱼抗体合成的强度也受复杂的遗传控制。

相似文献

1
Variability in humoral responses to DNP-KLH of rainbow trout (Salmo gairdneri). Comparison of antibody kinetics and immunoglobulins spectrotypes between normal trouts and trouts obtained by gynogenesis or self-fertilization.虹鳟(萨氏虹鳟)对二硝基苯-钥孔戚血蓝蛋白体液反应的变异性。正常虹鳟与通过雌核发育或自体受精获得的虹鳟之间抗体动力学和免疫球蛋白光谱类型的比较。
Dev Comp Immunol. 1986 Spring;10(2):207-17. doi: 10.1016/0145-305x(86)90004-2.
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Antibody diversity in trouts obtained by gynogenesis or self-fertilization. Comparative analysis of the heavy chain spectrotypes.
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Primary in vitro stimulation of antibody production by rainbow trout lymphocytes.
Vet Immunol Immunopathol. 1986 Jun;12(1-4):29-38. doi: 10.1016/0165-2427(86)90107-8.
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Effect of different adjuvants on the humoral immune response of rainbow trout.不同佐剂对虹鳟鱼体液免疫反应的影响。
Dev Comp Immunol. 1985 Winter;9(1):141-6. doi: 10.1016/0145-305x(85)90067-9.
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Opsonic effect of rainbow trout (Salmo gairdneri) antibody on phagocytosis of Yersinia ruckeri by trout leukocytes.
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The immune response in immunized and naturally infected rainbow trout (Salmo gairdneri) to Diplostomum spathaceum as detected by enzyme-linked immunosorbent assay (ELISA).通过酶联免疫吸附测定(ELISA)检测免疫和自然感染的虹鳟鱼(Salmo gairdneri)对剑带双穴吸虫的免疫反应。
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[Obtaining an anti-trout (Salmo gairdneri Rich.) immunoglobulin specific serum from rabbits immunized with the slowest serum fraction isolated in polyacrylamide gel electrophoresis].[从用聚丙烯酰胺凝胶电泳中分离出的最慢血清组分免疫的兔获得抗虹鳟鱼(Salmo gairdneri Rich.)免疫球蛋白特异性血清]
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Induction of nonspecific immunosuppression in a primitive teleost, rainbow trout (Salmo gairdneri).在一种原始硬骨鱼虹鳟(Salmo gairdneri)中诱导非特异性免疫抑制。
Dev Comp Immunol. 1984 Summer;8(3):569-78. doi: 10.1016/0145-305x(84)90089-2.

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