Cossarini-Dunier M, Desvaux F X, Dorson M
Dev Comp Immunol. 1986 Spring;10(2):207-17. doi: 10.1016/0145-305x(86)90004-2.
The anti-DNP antibody responses were compared between conventional trouts produced in fishfarm and trouts experimentally obtained by self-fertilization of hermaphrodites or by gynogenesis. The variability of anti-DNP antibody titres was equivalent between normal and gynogenetic fish, but significantly reduced for fish obtained by self-fertilization. Isoelectrofocusing analysis of individually-isolated anti-DNP antibodies indicate low molecular heterogeneity but large variability between conventional trouts. Almost complete sharing of individual spectrotypes was observed between self-fertilized fish and large similarities between gynogenetics animals. These results suggest that the intensity of antibody synthesis in trout is under a complex genetic control, even in inbred animals expressing large similarities in their antibody repertoires.
对养殖场养殖的传统虹鳟鱼与通过雌雄同体自体受精或雌核发育实验获得的虹鳟鱼的抗二硝基苯酚(DNP)抗体反应进行了比较。正常鱼和雌核发育鱼的抗DNP抗体滴度变异性相当,但自体受精获得的鱼的变异性显著降低。对单独分离的抗DNP抗体进行等电聚焦分析表明,传统虹鳟鱼之间存在低分子异质性但变异性很大。在自体受精的鱼之间观察到几乎完全相同的个体光谱类型,在雌核发育动物之间也有很大的相似性。这些结果表明,即使在抗体库有很大相似性的近交动物中,虹鳟鱼抗体合成的强度也受复杂的遗传控制。