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基于互联网和编程技术的分化型甲状腺癌术后患者个体化管理的可行性研究。

Feasibility study on individualized management of postoperative patients with differentiated thyroid cancer based on internet and programming technology.

机构信息

Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, No. 119 Nansihuan West Road, Fengtai District, Beijing, 100070, China.

Department of Endocrinology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

出版信息

J Cancer Res Clin Oncol. 2023 Oct;149(13):12405-12412. doi: 10.1007/s00432-023-05078-2. Epub 2023 Jul 13.

DOI:10.1007/s00432-023-05078-2
PMID:37438541
Abstract

PURPOSE

To explore the feasibility of individualized management of postoperative patients with differentiated thyroid cancer by a mode based on internet and programming technology.

METHODS

The enrolled patients were randomly divided into the study group and the control group. The study group used a mobile application to collect patient information, evaluate the risk of thyroid cancer recurrence and levothyroxine medication risk, develop individual thyrotropin control targets, and push levothyroxine adjustment recommendations to patients. In the control group, the traditional outpatient follow-up mode was used.

RESULTS

Two hundred patients were randomly divided into the study group and the control group at a 1:1 ratio. There was no significant difference in the physical and chemical indices between the two groups at baseline. During the 1-year follow-up, there was no significant difference in the thyrotropin attainment rate, heart rate or bone mineral density between the study group and the control group. During the 2-year follow-up, the thyrotropin attainment rate of the study group was better than that of the control group. The total score of Symptom Checklist 90 of the study group was lower than the control group, and satisfaction with the treatment was significantly higher than that of the control group.

CONCLUSION

The management based on the internet and programming technology is not inferior to the traditional outpatient follow-up mode, and is beneficial to improve patients' quality of life, promote the implementation of the national graded diagnosis and treatment system and the grassroots management of chronic diseases.

摘要

目的

探索基于互联网和编程技术的个体化管理模式在分化型甲状腺癌术后患者管理中的应用。

方法

将患者随机分为研究组和对照组。研究组使用移动应用程序收集患者信息,评估甲状腺癌复发和左旋甲状腺素用药风险,制定个体化促甲状腺激素控制目标,并向患者推送左旋甲状腺素调整建议。对照组采用传统的门诊随访模式。

结果

200 例患者按 1∶1 随机分组,两组基线时理化指标无显著差异。在 1 年随访期间,两组促甲状腺激素达标率、心率或骨密度无显著差异。在 2 年随访期间,研究组的促甲状腺激素达标率优于对照组。研究组的症状自评量表 90 项总分为低于对照组,对治疗的满意度明显高于对照组。

结论

基于互联网和编程技术的管理模式并不逊于传统的门诊随访模式,有利于提高患者的生活质量,促进国家分级诊疗制度和基层慢性病管理的实施。

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Current Controversies in Low-Risk Differentiated Thyroid Cancer: Reducing Overtreatment in an Era of Overdiagnosis.低危分化型甲状腺癌的当前争议:在过度诊断时代减少过度治疗。
J Clin Endocrinol Metab. 2023 Jan 17;108(2):271-280. doi: 10.1210/clinem/dgac646.
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Application and prospect of trabecular bone score in differentiated thyroid cancer patients receiving thyrotropin suppression therapy.
促甲状腺激素抑制治疗分化型甲状腺癌患者中骨小梁评分的应用及前景。
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Predictors of Anxiety and Depression in Differentiated Thyroid Cancer Survivors: Results of a Cross-Sectional Study.分化型甲状腺癌幸存者焦虑和抑郁的预测因素:一项横断面研究的结果。
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Prevalence and predictors of psychological distress among patients with thyroid cancer during transitional period in China: a cross-sectional study.中国甲状腺癌患者过渡期心理困扰的患病率及其预测因素:一项横断面研究。
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