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[衰弱表型与睡眠障碍的风险因素]

[Frailty phenotype and risk factor for disturbed sleep].

作者信息

Frohnhofen Helmut, Stenmanns Carla, Gronewold Janine, Mayer Geert

机构信息

Klinik für Orthopädie und Unfallchirurgie, Heinrich Heine Universität Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.

Klinik für Neurologie, Universitätsklinikum Essen, Hufelandstr. 55, 45147, Essen, Deutschland.

出版信息

Z Gerontol Geriatr. 2023 Nov;56(7):551-555. doi: 10.1007/s00391-023-02219-7. Epub 2023 Jul 12.

Abstract

Regardless of the nature of its operationalization, frailty has significant negative consequences for the person concerned and the community. Even if a generally accepted definition of frailty is still missing, there is no doubt about the existence of this phenomenon. Pathophysiologically, a dysfunctional interaction between multiple complex systems is discussed. Therapeutic interventions show that frailty is a dynamic state that can be improved. The pathophysiological characteristics of frailty and sleep disturbances show numerous similarities. In addition, the risk of frailty is increased in individuals with sleep disturbances. As the majority of sleep disorders can usually be well treated, screening for sleep disorders should be integrated into a comprehensive concept of management of frailty.

摘要

无论衰弱的操作化定义如何,它都会给相关个人和社区带来重大负面影响。尽管目前仍缺乏一个被普遍接受的衰弱定义,但这一现象的存在是毋庸置疑的。从病理生理学角度来看,人们讨论了多个复杂系统之间的功能失调性相互作用。治疗干预表明,衰弱是一种可以改善的动态状态。衰弱和睡眠障碍的病理生理特征有许多相似之处。此外,睡眠障碍患者发生衰弱的风险会增加。由于大多数睡眠障碍通常都能得到很好的治疗,因此睡眠障碍筛查应纳入衰弱综合管理概念中。

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