Unidad de Investigación Epidemiológica y en Servicios de Salud, Área Envejecimiento, Instituto Mexicano del Seguro Social, Cuidad de México, Mexico.
Center for Evaluation Research and Surveys, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
BMC Geriatr. 2021 Jun 16;21(1):368. doi: 10.1186/s12877-021-02272-0.
The association between sleep duration and frailty remains unconclusive since most of the studies have been cross-sectional. Therefore, this study aimed to analyze the association between sleep duration, sleep complaints, and incident frailty.
A community-based cohort study from rural areas in Mexico with 309 older adults aged 70 and over. Data from waves two and three of the Rural Frailty Study were used. We operationalized the Fried frailty phenotype to describe prevalent and incident frailty at two consecutive waves. Sleep duration was classified as: ≤ 5 h, 6 h, 7-8 h, and ≥ 9 h; and the self-reported sleep complaints as a dichotomous variable. Analyses were performed using Poison regression models.
The average age was 76.2 years and 55.3% were women; the incidence of frailty was 30.4%; 13.3% slept ≤5 h, and 38.5% ≥ 9 h. Compared with the group that slept 7-8 h, the risk of frailty at 4.4 years of follow-up was significantly higher among those who slept ≤5 h (adjusted RR 1.80, 95% CI: 1.04-3.11) and among those who slept ≥9 h (adjusted RR 1.69, 95% CI: 1.10-2.58). Sleep complaints were not associated with incident frailty (adjusted RR 1.41, 95% CI: 0.94-2.12).
Our results show that short and long sleep duration are associated with the incidence of frailty. Studies that objectively evaluate sleep duration are needed to clarify whether meeting the recommended hours of sleep decreases frailty incidence.
由于大多数研究都是横断面研究，因此睡眠持续时间与虚弱之间的关联仍不确定。因此，本研究旨在分析睡眠持续时间、睡眠抱怨与虚弱事件之间的关系。
这是一项来自墨西哥农村地区的基于社区的队列研究，共有 309 名 70 岁及以上的老年人。使用了农村虚弱研究的第二波和第三波的数据。我们采用 Fried 虚弱表型来描述连续两次波中的现患和新发虚弱。睡眠持续时间分为：≤5 小时、6 小时、7-8 小时和≥9 小时；自我报告的睡眠抱怨为二分类变量。使用泊松回归模型进行分析。
平均年龄为 76.2 岁，55.3%为女性；虚弱的发生率为 30.4%；13.3%的人睡眠时间≤5 小时，38.5%的人睡眠时间≥9 小时。与睡眠 7-8 小时的组相比，在 4.4 年的随访中，睡眠时间≤5 小时的人发生虚弱的风险明显更高（调整后的 RR 1.80，95%CI：1.04-3.11），睡眠时间≥9 小时的人发生虚弱的风险也更高（调整后的 RR 1.69，95%CI：1.10-2.58）。睡眠抱怨与虚弱的发生无关（调整后的 RR 1.41，95%CI：0.94-2.12）。
我们的结果表明，短时间和长时间睡眠与虚弱的发生有关。需要进行客观评估睡眠持续时间的研究，以明确是否达到推荐的睡眠时间可以降低虚弱的发生率。
