Montemurro D, Ronzani G, Defilippi G, Pizzuti A, Brusca A
G Ital Cardiol. 1986 Apr;16(4):308-12.
The association between a calcified mitral annulus and impairment of cardiac impulse transmission is well known. However informations on the relations between the site of mitral calcification and conduction disturbance are still scanty. Twenty-nine patients (22 women and 7 men, mean age 64.4 +/- 13.1 years) with M-mode and two-dimensional echocardiographic evidence of mitral annulus calcifications were studied. The "annulus" was subdivided in 4 segments: antero-medial, antero-lateral, postero-medial and postero-lateral. Conduction disturbances were present in 15 patients (51.7%). Atrio-ventricular or intra-ventricular conduction defects were found in 12 out of 15 patients with calcifications of the antero-medial segment and only in 3 of 14 subjects without antero-medial calcifications (P less than .01). The presence of conduction defects therefore seems to be significantly increased when calcium deposition is located near the conduction system.
二尖瓣环钙化与心脏冲动传导受损之间的关联已广为人知。然而，关于二尖瓣钙化部位与传导障碍之间关系的信息仍然匮乏。对29例（22例女性和7例男性，平均年龄64.4±13.1岁）经M型和二维超声心动图证实有二尖瓣环钙化的患者进行了研究。“瓣环”被细分为4个节段：前内侧、前外侧、后内侧和后外侧。15例患者（51.7%）存在传导障碍。在前内侧节段钙化的15例患者中，有12例发现房室或室内传导缺陷，而在无前内侧钙化的14例受试者中仅3例有此类缺陷（P<0.01）。因此，当钙沉积位于传导系统附近时，传导缺陷的发生率似乎会显著增加。
