Dyer Andrew, Böhnke Jan R, Curran David, McGrath Katie, Toner Paul
Centre for Improving Health-Related Quality of Life, School of Psychology, Queen's University Belfast, Belfast, UK.
School of Health Sciences, University of Dundee, Dundee, UK.
Drug Alcohol Rev. 2023 Nov;42(7):1680-1700. doi: 10.1111/dar.13717. Epub 2023 Jul 13.
Consideration of an individual's quality of life (QoL) can benefit assessment and treatment of addictive disorders, however, uncertainty remains over operationalisation of the construct as an outcome and the appropriateness of existing measures for these populations. This systematic review aimed to identify and evaluate QoL and health-related QoL outcome instruments used in addiction-related risk and harm research and map their conceptualised domains.
Three electronic databases and a specialised assessment library were searched on 1 February 2022 for QoL or health-related QoL outcome instruments used with addiction-related risk and harm populations. PRISMA reporting guidance was followed and included outcome instruments were appraised using mixed methods. Psychometric evidence supporting their use was summarised. The COSMIN risk of bias tool was used to assess validation studies.
A total of 298 articles (330 studies) used 53 outcome instruments and 41 unique domains of QoL. Eleven instruments' psychometric properties were evaluated. No instrument was assessed for any parameter in at least five studies for meta-analytic pooling. Cronbach's alpha (α) internal consistency was the most widely assessed parameter with the AQoLS, WHOQOL-BREF, ALQoL-9, Q-LES-Q-SF, SF-12, DUQoL, QLI and SF-36 displaying promising statistics (α > 0.70).
Many instruments have been utilised. However, a significant proportion of studies applied a small number of instruments with minimal high-quality validation evidence supporting their use within addiction-related risk and harm. Promising instruments are recommended, however, the paucity of supporting evidence limits confidence in the reliability and validity of QoL measurement in these populations.
考虑个体的生活质量（QoL）有助于成瘾性疾病的评估和治疗，然而，作为一项结果指标，该概念的操作化仍存在不确定性，且现有测量方法对这些人群的适用性也不明确。本系统评价旨在识别和评估用于成瘾相关风险和危害研究的生活质量及健康相关生活质量结果指标，并梳理其概念化领域。
于2022年2月1日在三个电子数据库和一个专业评估库中检索用于成瘾相关风险和危害人群的生活质量或健康相关生活质量结果指标。遵循PRISMA报告指南，对纳入的结果指标采用混合方法进行评估。总结支持其使用的心理测量证据。使用COSMIN偏倚风险工具评估验证研究。
共有298篇文章（330项研究）使用了53个结果指标和41个独特的生活质量领域。对11个指标的心理测量特性进行了评估。没有任何一个指标在至少五项研究中针对任何参数进行了元分析合并评估。Cronbach's α内部一致性是评估最广泛的参数，AQoLS、WHOQOL-BREF、ALQoL-9、Q-LES-Q-SF、SF-12、DUQoL、QLI和SF-36显示出有前景的统计数据（α>0.70）。
已使用了许多指标。然而，相当一部分研究使用的指标数量较少，且在成瘾相关风险和危害研究中支持其使用的高质量验证证据极少。推荐了有前景的指标，然而，支持证据的匮乏限制了对这些人群生活质量测量的可靠性和有效性的信心。
