Achkar E, Carey W D, Petras R, Sivak M V, Revta R
Gastrointest Endosc. 1986 Aug;32(4):278-81. doi: 10.1016/s0016-5107(86)71846-4.
Small bowel mucosal biopsy specimens were studied in 52 consecutive patients. Twenty-six patients underwent biopsy by a suction capsule and 16 patients by endoscopy using an 8-mm forceps. Additionally, 10 patients were asked to undergo biopsy by both techniques in the same morning. Material was obtained in 81% of attempts by suction and 100% by endoscopy. Tissue obtained was excellent in 58%, good in 28%, and poor in 14% of suction biopsy specimens. Corresponding grades for endoscopy were 65%, 31%, and 4%. The frequency of abnormal findings was not different by either technique. In the 10 patients who had both procedures, mean time to completion was 43 min by suction and 12 min by endoscopy. Intravenous premedication was used in endoscopy, and patient comfort was judged as excellent in 60% with endoscopy, whereas 60% judged suction biopsy as very uncomfortable. The mean fluoroscopy time of 3.9 min necessary for suction biopsy was eliminated with endoscopy. Biopsy with an 8-mm forceps through the endoscope is the preferred way to obtain tissue from the proximal small bowel.
对52例连续患者的小肠黏膜活检标本进行了研究。26例患者通过抽吸胶囊进行活检，16例患者通过使用8毫米活检钳的内镜检查进行活检。此外，10例患者被要求在同一天上午通过两种技术进行活检。抽吸活检81%的尝试获得了标本，内镜检查100%获得了标本。抽吸活检标本中，58%的组织质量优秀，28%良好，14%较差。内镜检查的相应等级分别为65%、31%和4%。两种技术发现异常的频率没有差异。在10例同时进行两种操作的患者中，抽吸活检完成的平均时间为43分钟，内镜检查为12分钟。内镜检查使用了静脉术前用药，60%的患者认为内镜检查时舒适度优秀，而60%的患者认为抽吸活检非常不舒服。内镜检查消除了抽吸活检所需的平均3.9分钟的透视时间。通过内镜使用8毫米活检钳进行活检是从小肠近端获取组织的首选方法。
