Master's Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia.
Physiology Department, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia.
Biomed Eng Online. 2023 Jul 13;22(1):70. doi: 10.1186/s12938-023-01128-5.
Tube misplacement into the tracheobronchial tract is associated with pneumothorax in 0.5% of cases. NGT verification only detects the position of the tube at the end of the procedure. Therefore, a safe nasogastric tube (SNGT) was created to detect the NGT position in real time in a simple and inexpensive way. This study aimed to prove the effectiveness of the SNGT prototype in Macaca fascicularis.
An SNGT producing 50% of the TV had 100% sensitivity and specificity in detecting the position of the tube at 100% of the TV, with a sensitivity of 100% and a specificity of 87.5%. There was a significant difference between the movement of the SNGT 50% TV and SNGT 100% TV airbags (p ≤ 0.05). However, there was no significant difference between the accuracy of placement of the 50% TV SNGT, 100% TV SNGT, and conventional NGT (p > 0.05). The pepsin enzyme had better sensitivity (100%) than pH paper (91.66%) in detecting the end-of-procedure tube position. This research has the potential to advance into human clinical trials.
SNGTs are highly effective in detecting the NGT position inside the respiratory and digestive tracts to prevent misplacement.
气管内导管（NGT）误入气管-支气管tract 可导致气胸，发生率约为 0.5%。NGT 验证仅能检测到操作结束时导管的位置。因此，我们研发了一种安全型 NGT（SNGT），以简单且经济的方式实时检测 NGT 位置。本研究旨在证明 SNGT 原型在食蟹猴中的有效性。
当 SNGT 产生 50%的 TV 时，在检测 100%的 TV 位置时，其灵敏度和特异性均为 100%，灵敏度为 100%，特异性为 87.5%。SNGT 50% TV 和 SNGT 100% TV 气袋的运动之间存在显著差异（p ≤ 0.05）。然而，50% TV SNGT、100% TV SNGT 和传统 NGT 的放置准确性之间没有显著差异（p > 0.05）。胃蛋白酶在检测操作结束时导管位置方面的灵敏度（100%）优于 pH 试纸（91.66%）。该研究具有推进至人体临床试验的潜力。
SNGT 可高度有效地检测 NGT 在呼吸道和消化道内的位置，以防止误置。
