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诱导膜技术治疗感染性胫骨骨缺损:回顾性研究。

Induced membrane technique in the treatment of infected tibial bone defect: A retrospective study.

机构信息

The First School of Clinical Medicine, Southern Medical University, Guangzhou, China.

Department of Orthopedics, Guangdong Second Provincial General Hospital, Guangzhou, China.

出版信息

Medicine (Baltimore). 2023 Jul 14;102(28):e34280. doi: 10.1097/MD.0000000000034280.

Abstract

To investigate the effect of the induced membrane technique (IMT) in the treatment of infected tibial bone defect. IMT is a 2-stage procedure dedicated to reconstruction of bone defects of the limbs. Treating injuries of the tibia characterized by segmental bone loss, severe damage to the soft tissue, and a conjoining infection is a challenge using IMT. A retrospective study was performed among the patients treated using IMT for infected tibial bone defect between 2017 and 2020. The complications were recorded, and the bone defect union and the functional results were evaluated by Paley method. All patients were followed up for at least 1 year. We included 12 patients (11 males) with a mean age of 44.5 years (range 19-65). The mean length of bone defect was 26.7 mm (range 10-60). The mean interval between the stage 1 and the stage 2 of the procedure was 11.8 weeks (range 4-32). At a mean follow-up of 18.08 months (range 12-32), bone union was achieved in all cases in a mean time of 8 months (range 5-16) without infection recurrence, where 1 patient received additional bone grafting. The joint function recovered well for the patients and the rate of functionally excellent and good results was 9/12. IMT in the treatment of infected tibial bone defect offers the advantages of simple operation, use of a smaller amount of autograft bone, and low recurrence rate of infection.

摘要

探讨诱导膜技术(IMT)在治疗感染性胫骨骨缺损中的作用。IMT 是一种 2 期手术,专门用于重建四肢的骨缺损。使用 IMT 治疗胫骨损伤具有节段性骨丢失、严重软组织损伤和合并感染的特点,这是一个挑战。对 2017 年至 2020 年间采用 IMT 治疗感染性胫骨骨缺损的患者进行回顾性研究。记录并发症,并采用 Paley 法评估骨缺损愈合和功能结果。所有患者均至少随访 1 年。我们纳入了 12 例(11 例男性)患者,平均年龄为 44.5 岁(19-65 岁)。骨缺损的平均长度为 26.7mm(10-60mm)。第 1 期和第 2 期之间的平均间隔为 11.8 周(4-32 周)。平均随访 18.08 个月(12-32 个月)后,所有患者均在 8 个月(5-16 个月)内实现了骨愈合,无感染复发,其中 1 例患者接受了额外的植骨。患者的关节功能恢复良好,功能优良率为 9/12。IMT 治疗感染性胫骨骨缺损具有操作简单、自体骨用量少、感染复发率低等优点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be10/10344485/59095eb2322d/medi-102-e34280-g001.jpg

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