Dumitriu Anca Silvia, Păunică Stana, Nicolae Ximena Anca, Bodnar Dana Cristina, Albu Ștefan Dimitrie, Suciu Ioana, Ciongaru Dragoș Nicolae, Giurgiu Marina Cristina
Department of Periodontology, Faculty of Dental Medicine, University of Medicine and Pharmacy "Carol Davila", 37 Dionisie Lupu Street, 020021 Bucharest, Romania.
Doctoral School, Faculty of Dental Medicine, University of Medicine and Pharmacy "Carol Davila", 37 Dionisie Lupu Street, 020021 Bucharest, Romania.
Healthcare (Basel). 2023 Jul 3;11(13):1918. doi: 10.3390/healthcare11131918.
(1) Background: The aim of the study was to evaluate the benefit of combining chlorhexidine with the mechanical treatment of peri-implant mucositis. (2) Methods: Articles from 2016 to 2021 included in the PubMed and Scopus databases were analyzed, following the PICOS criteria and the randomized controlled study model that used chlorhexidine in various forms in the treatment of peri-mucositis. According to the established criteria, a limited number of studies were selected. These studies had as their criteria of evaluation for the effectiveness of chlorhexidine, plaque indices, bleeding indices and depth probing indices. Chlorhexidine has been used after mechanical debridement as a solution, with different concentrations of 0.06%/0.12%/0.2% alone or in a concentration of 0.03%, in combination with 0.05% cetylpyridinium chloride, as well as in the form of a gel with a concentration of 0.2%. (3) Results: The results were assessed to a placebo or other substances, and showed a significant reduction in the indices with a follow-up period ranging from 3 months to 1 year. (4) Conclusions: The association of chlorhexidine with the mechanical treatment of peri-implant mucositis has a role in reducing inflammation, although a complete remission was not obtained in all cases, and the results were not statistically significantly different from the use of other antiseptics.
(1) 背景：本研究的目的是评估洗必泰与种植体周围黏膜炎机械治疗相结合的益处。(2) 方法：分析了2016年至2021年纳入PubMed和Scopus数据库的文章，遵循PICOS标准以及在种植体周围黏膜炎治疗中使用各种形式洗必泰的随机对照研究模型。根据既定标准，选择了数量有限的研究。这些研究将洗必泰的有效性评估标准设定为菌斑指数、出血指数和探诊深度指数。机械清创后，洗必泰以溶液形式使用，浓度分别为0.06%/0.12%/0.2%，单独使用或浓度为0.03%，与0.05%的西吡氯铵联合使用，以及以浓度为0.2%的凝胶形式使用。(3) 结果：将结果与安慰剂或其他物质进行评估，结果显示在3个月至1年的随访期内各项指数显著降低。(4) 结论：洗必泰与种植体周围黏膜炎机械治疗相结合在减轻炎症方面有作用，尽管并非所有病例都能完全缓解，且结果与使用其他防腐剂相比无统计学显著差异。
