College of Landscape Architecture and Arts, Northwest A&F University, Xianyang 712100, China.
Int J Mol Sci. 2023 Jun 25;24(13):10609. doi: 10.3390/ijms241310609.
Tree peonies ( Section )-including nine wild species, which belong to subsections and -are economically important plants with ornamental, nutritional, and medicinal applications. In this study, for the first time, we determined the bioactive components and antioxidant activities and antibacterial activities of the newly grown leaves of nine wild tree peony species (WTPS). A total of 276 bioactive components were identified through non-targeted metabolomics; more than 80% of the 276 metabolites identified are terpenoids and flavonoids. A total of 42 differential metabolites were quantitatively determined. The main differential metabolites were Paeoniflorin, Luteoloside, Hyperin, Apigenin-7-glucoside, Rhoifolin, and Cantharidin. Such a high terpenoid and flavonoid content of the leaf extracts renders them as species with strong antibacterial capacities, and most of the bacteria tested showed greater sensitivity derived from the members of subsection than those of subsection . All WTPS have significant antioxidant activity; this activity is attributed to high levels of the total phenolic content (TPC) and total flavonoid content (TFC), of which, among the nine WTPS, has the strongest antioxidant capacity. Our results provided a theoretical basis for the in-deep application of tree peony leaves for food, medical, and pharmaceutical industries.
牡丹属（芍药属）-包括 9 个野生种，分属于 和 亚属-是具有观赏、营养和药用应用价值的经济重要植物。在这项研究中，我们首次确定了 9 种野生牡丹（WTPS）新生长叶片的生物活性成分、抗氧化活性和抗菌活性。通过非靶向代谢组学鉴定出了 276 种生物活性成分；所鉴定的 276 种代谢物中，超过 80%为萜类化合物和类黄酮。共定量测定了 42 种差异代谢物。主要差异代谢物为芍药苷、芦丁、金丝桃苷、芹菜素-7-葡萄糖苷、山奈酚、斑蝥素。叶片提取物中如此高的萜类化合物和类黄酮含量使它们具有很强的抗菌能力，而且大多数测试的细菌对来自 亚属的成员比来自 亚属的成员更敏感。所有 WTPS 都具有显著的抗氧化活性；这种活性归因于总酚含量（TPC）和总类黄酮含量（TFC）水平较高，其中，在 9 种 WTPS 中， 具有最强的抗氧化能力。我们的研究结果为牡丹叶在食品、医疗和制药行业的深入应用提供了理论基础。
