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夏威夷、英国和日本女性的甲状腺功能与乳腺癌发病率

Thyroid function and the incidence of breast cancer in Hawaiian, British and Japanese women.

作者信息

Thomas B S, Bulbrook R D, Goodman M J, Russell M J, Quinlan M, Hayward J L, Takatani O

出版信息

Int J Cancer. 1986 Sep 15;38(3):325-9. doi: 10.1002/ijc.2910380305.

DOI:10.1002/ijc.2910380305
PMID:3744589
Abstract

Serum-free thyroxine (FT4) concentrations are lower in Hawaiian and Hawaiian Caucasian women than in Hawaiian Japanese, Hawaiian Filipino, Hawaiian Chinese, and English and Japanese mainland women. There is a high inverse correlation between FT4 and risk of breast cancer in these ethnic groups. Thyroid-stimulating hormone (TSH) concentrations, which are inversely correlated with FT4, generally show the same relationship.

摘要

夏威夷女性和夏威夷白种女性的血清游离甲状腺素(FT4)浓度低于夏威夷日裔、夏威夷菲律宾裔、夏威夷华裔以及英国和日本本土女性。在这些种族群体中,FT4与乳腺癌风险呈高度负相关。促甲状腺激素(TSH)浓度与FT4呈负相关,通常也呈现相同的关系。

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