Institute of Quality Standard and Monitoring Technology for Agro-Products of Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Key Laboratory of Testing and Evaluation for Agro-Product Safety and Quality, Ministry of Agriculture and Rural Affairs, Guangzhou 510640, China.
Int J Mol Sci. 2023 Jul 3;24(13):11031. doi: 10.3390/ijms241311031.
Arsenic (As) is a metalloid environmental pollutant ubiquitous in nature that causes chronic and irreversible poisoning to humans through its bioaccumulation in the trophic chain. Rice, the staple food crop for 350 million people worldwide, accumulates As more easily compared to other cereal crops due to its growth characteristics. Therefore, an in-depth understanding of the molecular regulatory mechanisms underlying As uptake, transport, and detoxification in rice is of great significance to solving the issue of As bioaccumulation in rice, improving its quality and safety and protecting human health. This review summarizes recent studies on the molecular mechanisms of As toxicity, uptake, transport, redistribution, regulation, and detoxification in rice. It aims to provide novel insights and approaches for preventing and controlling As bioaccumulation in rice plants, especially reducing As accumulation in rice grains.
砷（As）是一种类金属环境污染物，在自然界中广泛存在，通过在食物链中的生物积累对人类造成慢性和不可逆转的毒害。水稻是全球 3.5 亿人的主食作物，由于其生长特点，比其他谷类作物更容易积累砷。因此，深入了解水稻中砷的吸收、运输和解毒的分子调控机制，对于解决水稻中砷的生物积累问题、提高其质量和安全性以及保护人类健康具有重要意义。本综述总结了近年来关于水稻中砷毒性、吸收、运输、再分配、调控和解毒的分子机制的研究，旨在为防止和控制水稻中砷的生物积累，特别是减少砷在水稻籽粒中的积累，提供新的见解和方法。
