Research Center for Environmental Membrane Biology and Department of Horticulture, Foshan University, Foshan, Guangdong 528000, China.
Faculty of Biological Sciences, University of Wroclaw, 50-328 Wroclaw, Poland.
Trends Plant Sci. 2023 Aug;28(8):880-892. doi: 10.1016/j.tplants.2023.03.008. Epub 2023 Mar 29.
Arsenic (As) is harmful to all living organisms, including humans and plants. To limit As uptake and avoid its toxicity, plants employ systems that regulate the uptake of As from the soil and its translocation from roots to grains. Ubiquitination, a highly conserved post-translational modification (PTM) in all eukaryotes, plays crucial roles in modulating As detoxification mechanisms in budding yeast (Saccharomyces cerevisiae), but little is known about its roles in As tolerance and transport in plants. In this opinion article we review recent findings and suggest that ubiquitination plays a crucial role in regulating As transport in plants. We also propose ideas for future research to explore the importance of ubiquitination for enhancing As tolerance in crops.
砷 (As) 对包括人类和植物在内的所有生物都是有害的。为了限制砷的吸收并避免其毒性，植物采用了一些系统来调节从土壤中吸收砷及其从根部向谷物的转运。泛素化是所有真核生物中高度保守的一种翻译后修饰（PTM），在调节出芽酵母（酿酒酵母）中的砷解毒机制中起着至关重要的作用，但对于其在植物中砷耐受和转运中的作用知之甚少。在这篇观点文章中，我们回顾了最近的发现，并提出泛素化在调节植物中砷转运方面起着关键作用。我们还提出了未来研究的思路，以探索泛素化在提高作物砷耐受性方面的重要性。
