Czene Szabolcs, Jegenyes Nikoletta, Krafcsik Olga, Lenk Sándor, Czigány Zsolt, Bortel Gábor, Kamarás Katalin, Rohonczy János, Beke David, Gali Adam
Doctoral School on Materials Sciences and Technologies, Óbuda University, Bécsi út 96/b, H-1034 Budapest, Hungary.
Wigner Research Centre for Physics, Institute for Solid State Physics and Optics, P.O. Box 49, H-1525 Budapest, Hungary.
Nanomaterials (Basel). 2023 Jun 27;13(13):1953. doi: 10.3390/nano13131953.
Silicon carbide nanoparticles (SiC NPs) are promising inorganic molecular-sized fluorescent biomarkers. It is imperative to develop methods to functionalize SiC NPs for certain biological applications. One possible route is to form amino groups on the surface, which can be readily used to attach target biomolecules. Here, we report direct amino-termination of aqueous SiC NPs. We demonstrate the applicability of the amino-terminated SiC NPs by attaching bovine serum albumin as a model for functionalization. We monitor the optical properties of the SiC NPs in this process and find that the fluorescence intensity is very sensitive to surface termination. Our finding may have implications for a few nanometers sized SiC NPs containing paramagnetic color centers with optically read electron spins.
碳化硅纳米颗粒（SiC NPs）是很有前景的无机分子尺寸荧光生物标志物。开发使SiC NPs功能化以用于特定生物应用的方法势在必行。一种可能的途径是在表面形成氨基，氨基可方便地用于连接目标生物分子。在此，我们报道了水性SiC NPs的直接氨基封端。我们通过连接牛血清白蛋白作为功能化模型来证明氨基封端的SiC NPs的适用性。我们在此过程中监测SiC NPs的光学性质，发现荧光强度对表面封端非常敏感。我们的发现可能对含有具有光学读取电子自旋的顺磁色心的几纳米尺寸的SiC NPs有影响。
