Zinc Oxide Quantum Dots May Provide a Novel Potential Treatment for Antibiotic-Resistant in .

is a significant pathogen that can affect both human beings and animals. The extensive current use of antibiotics has resulted in antibiotic resistance. In our previous research, we found that zinc oxide quantum dots (ZnO QDs) had inhibitory effects on antibiotic-resistant microorganisms. In this study, a strain of with a broad antibiotic-resistant spectrum was isolated and identified from at Sichuan Agricultural University Teaching Animal Hospital. The genome for the resistance and virulence genes was analyzed. Additionally, the antibacterial effects and anti-virulence mechanism of ZnO QDs for were investigated. The results showed that the genome of is 1,943,955 bp, containing 22 resistance genes and 95 virulence genes. ZnO QDs have a good antibacterial effect against by reducing bacterial growth and decreasing the expression of virulence genes, including , , , and , which provides a novel potential treatment for .