Weizman Z, Mussaffi H
Int J Pediatr Otorhinolaryngol. 1986 Apr;11(2):147-51. doi: 10.1016/s0165-5876(86)80009-x.
Seventy-two children with periorbital cellulitis were followed prospectively during a 30-month study period. Twenty patients (28%) had mucopurulent rhinorrhea with obvious radiological ipsilateral opacity of the ethmoid sinuses. This group of patients, as opposed to patients with periorbital cellulitis and no associated ethmoiditis, is characterized by the following features: Higher incidence of temperature greater than 38.5 degrees C (16/20 vs 24/52. P less than 0.01) and elevated white blood count greater than 15,000 cells/mm3 on admission (10/20 vs 5/52. P less than 0.001). Delayed recovery (6.7 +/- 3.4 vs 3.4 +/- 1.6 days. P less than 0.001). Higher rate of recurrent periorbital cellulitis with associated ethmoiditis within 6 months of follow-up (5/20 vs 1/52. P less than 0.01). This ethmoiditis-associated serious form of periorbital cellulitis requires an aggressive treatment regimen and a prolonged follow-up.
在一项为期30个月的前瞻性研究中，对72例眶周蜂窝织炎患儿进行了随访。20例患者（28%）有黏液脓性鼻漏，筛窦有明显的同侧放射学混浊。与无相关筛窦炎的眶周蜂窝织炎患者相比，这组患者具有以下特征：体温高于38.5摄氏度的发生率更高（16/20比24/52，P<0.01），入院时白细胞计数高于15000/mm³（10/20比5/52，P<0.001）。恢复延迟（6.7±3.4天比3.4±1.6天，P<0.001）。随访6个月内伴有筛窦炎的眶周蜂窝织炎复发率更高（5/20比1/52，P<0.01）。这种与筛窦炎相关的严重眶周蜂窝织炎需要积极的治疗方案和延长随访时间。
