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关于死藤水治疗效果的系统评价。

A Systematic Review on the Therapeutic Effects of Ayahuasca.

作者信息

Gonçalves Joana, Luís Ângelo, Gallardo Eugenia, Duarte Ana Paula

机构信息

Centro de Investigação em Ciências da Saúde (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.

Laboratório de Fármaco-Toxicologia, UBIMedical, Universidade da Beira Interior, Estrada Municipal 506, 6200-284 Covilhã, Portugal.

出版信息

Plants (Basel). 2023 Jul 7;12(13):2573. doi: 10.3390/plants12132573.

DOI:10.3390/plants12132573
PMID:37447135
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10346174/
Abstract

Traditional therapies, resorting to the use of plants, have acquired a great demand over the years, both for economic reasons and the preference for natural treatments. Some studies suggest that ayahuasca may have beneficial properties in treating some physical and psychological imbalances. Thus, we carried out a systematic review of studies published up to December 2022, where these themes were addressed. The search was carried out in the PubMed database, and only studies written in English and published in peer-reviewed journals were included. Thus, 228 publications were identified, of which 66 were included in the present study. The reviewed studies suggest that ayahuasca may have beneficial effects on various physical and psychological conditions, namely in the treatment of depression, anxiety and various diseases of the neurobiological system, as well as anti-inflammatory and antimicrobial properties, demonstrating its therapeutic potential. The number of studies that address this issue has also been growing, demonstrating interest in the search for alternative treatments. However, to the best of our knowledge, this is the first systematic review where all the findings of therapeutic effects associated with the consumption of ayahuasca are reviewed.

摘要

多年来,出于经济原因以及对自然疗法的偏爱,采用植物的传统疗法需求量大增。一些研究表明,死藤水在治疗某些身心失调方面可能具有有益特性。因此,我们对截至2022年12月发表的涉及这些主题的研究进行了系统综述。检索在PubMed数据库中进行,仅纳入用英文撰写并发表在同行评审期刊上的研究。由此,共识别出228篇出版物,其中66篇纳入本研究。综述研究表明,死藤水可能对各种身心状况具有有益影响,即在治疗抑郁症、焦虑症以及各种神经生物学系统疾病方面,还具有抗炎和抗菌特性,展现出其治疗潜力。探讨该问题的研究数量也在不断增加,表明人们对寻找替代疗法很感兴趣。然而,据我们所知,这是首次对与饮用死藤水相关的所有治疗效果研究结果进行的系统综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99af/10346174/d69db4cfb849/plants-12-02573-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99af/10346174/d69db4cfb849/plants-12-02573-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99af/10346174/d69db4cfb849/plants-12-02573-g001.jpg

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Metabolomics and integrated network analysis reveal roles of endocannabinoids and large neutral amino acid balance in the ayahuasca experience.
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