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有氧运动训练与地中海饮食相结合与意大利老年人肌少症患病率降低无关。

Combined Aerobic Training and Mediterranean Diet Is Not Associated with a Lower Prevalence of Sarcopenia in Italian Older Adults.

机构信息

Department of Geriatrics, Orthopedics, and Rheumatology, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

Fondazione Policlinico Universitario "A. Gemelli", IRCCS, 00168 Rome, Italy.

出版信息

Nutrients. 2023 Jun 29;15(13):2963. doi: 10.3390/nu15132963.

Abstract

Previous studies found a lower prevalence of sarcopenia in older adults engaged in regular aerobic training (AT) or with greater adherence to a Mediterranean (MED) diet. However, the effect of their combination on sarcopenia indices is unknown. The present study tested the association between AT plus a MED diet and the presence of sarcopenia and its defining elements in a sample of Italian older adults enrolled in the Longevity Check-up 7+ (Lookup 7+) project. Analyses were conducted in participants 65+ years, with a body mass index of at least 18.5 kg/m, engaged in regular AT, and without missing information for the variables of interest. MED diet adherence was evaluated via a modified version of the MEDI-LITE score and categorized as low, moderate, or high. The presence of sarcopenia was established by handgrip strength and appendicular skeletal muscle mass (ASM) values below sex-specific cut-points recommended by the European Working Group on Sarcopenia in Older People 2. Data from 491 older adults were analyzed for the present study. The mean age was 72.7 ± 5.7 years, and 185 (37.7%) were women. MED diet adherence was low in 59 (12.0%) participants, moderate in 283 (57.6%), and high in 149 (30.3%). Sarcopenia was identified in 26 participants (5.3%), with no differences across MED diet adherence groups. The results of binary logistic regression showed no significant associations between AT plus adherence to a MED diet and dynapenia, low ASM, or sarcopenia. The findings of the present study indicate that the combination of AT with a MED diet is not associated with a lower probability of sarcopenia or its defining elements in Italian older adults enrolled in Lookup 7+. Further research is warranted to establish whether exercise frequency, volume, intensity, and length of engagement in AT impact the association between MED diet and sarcopenia.

摘要

先前的研究发现,经常进行有氧运动训练(AT)或更遵循地中海饮食(MED)的老年人中,肌少症的患病率较低。然而,他们的组合对肌少症指标的影响尚不清楚。本研究在参加长寿检查 7+(Lookup 7+)项目的意大利老年人样本中,检验了 AT 加 MED 饮食与肌少症及其定义元素的存在之间的关联。分析对象为年龄在 65 岁以上、体重指数至少为 18.5kg/m、经常进行规律 AT 且无感兴趣变量缺失信息的参与者。通过 MEDI-LITE 评分的改良版评估 MED 饮食的依从性,并分为低、中、高三种。肌少症的存在通过握力和四肢骨骼肌质量(ASM)值低于欧洲老年人肌少症工作组推荐的性别特异性切点来确定。本研究共分析了 491 名老年人的数据。平均年龄为 72.7 ± 5.7 岁,185 名(37.7%)为女性。59 名(12.0%)参与者的 MED 饮食依从性低,283 名(57.6%)为中等,149 名(30.3%)为高。26 名参与者(5.3%)存在肌少症,不同 MED 饮食依从性组之间无差异。二元逻辑回归结果显示,AT 加 MED 饮食依从性与无力、低 ASM 或肌少症之间无显著关联。本研究结果表明,在参加 Lookup 7+的意大利老年人中,AT 与 MED 饮食相结合与肌少症或其定义元素的低发生率无关。需要进一步的研究来确定 AT 的运动频率、量、强度和持续时间是否会影响 MED 饮食与肌少症之间的关联。

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