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儿童过敏症:我们了解多少?

's Allergy in Children: What Do We Know?

机构信息

Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy.

出版信息

Nutrients. 2023 Jul 4;15(13):3030. doi: 10.3390/nu15133030.

Abstract

allergy is an emerging pathological condition in both general and pediatric populations with a wide range of symptoms linked to variable molecular patterns, justifying systemic and cross-reactions with other allergens (i.e., latex, pollen, and fruit). Skin prick test (SPT), specific serum IgE (Act d 1, Act d 2, Act d 5, Act d 8, and Act d 10) directed against five out of thirteen molecular allergens described in the literature, and oral test challenge with are available for defining diagnosis. The management is similar to that of other food allergies, mostly based on an elimination diet. Although kiwi allergy has been on the rise in recent years, few studies have evaluated the clinical characteristics and methods of investigating this form of allergy. Data collected so far show severe allergic reaction to be more frequent in children compared to adults. Therefore, the aim of this review is to collect the reported clinical features and the available association with specific molecular patterns of recognition to better understand how to manage these patients and improve daily clinical practice.

摘要

过敏是一种在普通人群和儿科人群中都日益出现的病理状况,其症状范围广泛,与各种分子模式相关,这也解释了与其他过敏原(如乳胶、花粉和水果)的全身性和交叉反应。皮肤点刺试验(SPT)、针对文献中描述的 13 种分子过敏原中的 5 种的特异性血清 IgE(Act d 1、Act d 2、Act d 5、Act d 8 和 Act d 10)以及口服试验挑战,可用于确定诊断。管理方法与其他食物过敏相似,主要基于消除饮食。尽管猕猴桃过敏近年来有所增加,但很少有研究评估这种过敏形式的临床特征和调查方法。迄今为止收集的数据表明,与成人相比,儿童更易发生严重过敏反应。因此,本综述的目的是收集已报道的临床特征和与特定识别分子模式的相关性,以更好地了解如何管理这些患者并改善日常临床实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd15/10346195/9b8bd52f6867/nutrients-15-03030-g001.jpg

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