Technologies for Criminal Investigations, Saxion University of Applied Sciences, M.H. Tromplaan 28, 7513 AB Enschede, The Netherlands.
Police Academy, Arnhemseweg 348, 7334 AC Apeldoorn, The Netherlands.
Sensors (Basel). 2023 Jul 6;23(13):6201. doi: 10.3390/s23136201.
Already for some decades lateral flow assays (LFAs) are 'common use' devices in our daily life. Also, for forensic use LFAs are developed, such as for the analysis of illicit drugs and DNA, but also for the detection of explosives and body fluid identification. Despite their advantages, including ease-of-use, LFAs are not yet frequently applied at a crime scene. This review describes (academic) developments of LFAs for forensic applications, focusing on biological and chemical applications, whereby the main advantages and disadvantages of LFAs for the different forensic applications are summarized. Additionally, a critical review is provided, discussing why LFAs are not frequently applied within the forensic field and highlighting the steps that are needed to bring LFAs to the forensic market.
几十年来,侧向流检测(LFA)已成为我们日常生活中的“常用设备”。此外,还开发了用于法医检测的 LFA,例如用于分析非法药物和 DNA,以及检测爆炸物和体液识别。尽管侧向流检测具有使用方便等优点,但在犯罪现场尚未得到广泛应用。本综述描述了侧向流检测在法医应用方面的(学术)发展,重点介绍了生物和化学应用,总结了侧向流检测在不同法医应用中的主要优缺点。此外,还提供了批判性的回顾,讨论了为什么侧向流检测在法医领域没有得到广泛应用,并强调了将侧向流检测推向法医市场所需的步骤。