胱抑素C作为结节病潜在的血液生物标志物：一例报告

Cystatin C as a Potential Blood Biomarker for Sarcoidosis: A Case Report.

作者信息

Fukunaga Shohei, Itoga Kenichi, Sonoda Hirotaka, Hoshino Yuki, Yoshimura Ryuichi, Egawa Masahiro, Ito Takafumi, Tanabe Kazuaki

机构信息

Nephrology, Shimane University Hospital, Izumo, JPN.

Internal Medicine, Shimane University Faculty of Medicine, Izumo, JPN.

出版信息

Cureus. 2023 Jun 12;15(6):e40304. doi: 10.7759/cureus.40304. eCollection 2023 Jun.

DOI:10.7759/cureus.40304

PMID:37448407

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10337699/

Abstract

Sarcoidosis is a multi-organ medical condition that is characterized by the formation of granulomas. We aimed to identify a correlation between each sarcoidosis blood biomarker and cystatin C (Cys-C) in sarcoidosis patients. We report a case of a 60-year-old man with sarcoidosis. The correlation between his Cys-C and each blood biomarker level and that between each blood biomarker and serum creatinine levels were determined using linear regression. Serum Cys-C correlated with each blood biomarker of sarcoidosis, while creatinine did not. These findings suggest that Cys-C is a potential blood biomarker for sarcoidosis.

摘要

结节病是一种多器官疾病，其特征是形成肉芽肿。我们旨在确定结节病患者中每种结节病血液生物标志物与胱抑素C（Cys-C）之间的相关性。我们报告了一例60岁的结节病男性病例。使用线性回归确定了他的Cys-C与每种血液生物标志物水平之间以及每种血液生物标志物与血清肌酐水平之间的相关性。血清Cys-C与结节病的每种血液生物标志物相关，而肌酐则不然。这些发现表明Cys-C是结节病的一种潜在血液生物标志物。