Bacteremia in an Immunocompetent Patient with SARS-CoV-2 Infection: A Case Report.

We report a case of bacteremia in a 73-year-old patient with SARS-CoV-2 infection and right lower abdominal tenderness in China. The microbiological features and genomic epidemiological characteristics of worldwide were investigated to identify the possible sources of infection. Whole-genome sequencing of WD-I2 was performed using an Illumina NovaSeq 6000 platform. Phylogenetic analysis of WD-I2 and other publicly available isolates was performed and visualized using the interactive Tree of Life (iTOL) web server. The resistome of WD-I2 consists of two antimicrobial resistance genes (M and B), which explains the antimicrobial resistance trait to tetracycline and macrolides. Phylogenetic analysis showed that the strain closest to our isolated strain WD-I2 was SUG1069, recovered from a pig feces sample from Canada, which differed by 589 SNPs. To our knowledge, this is the first report of bacteremia in China. Our findings highlight the potential risk of invasive infections during the COVID-19 pandemic.