Massachusetts Eye Research and Surgery Institution, Waltham, Massachusetts, USA.
Department of Ophthalmology, Suddhavej Hospital, Faculty of Medicine, Mahasarakham University, Maha Sarakham, Thailand.
Ocul Immunol Inflamm. 2024 Sep;32(7):1494-1497. doi: 10.1080/09273948.2023.2232447. Epub 2023 Jul 14.
Suprachoroidal triamcinolone acetonide (SCS-TA) injections were recently approved to treat macular edema secondary to noninfectious uveitis. However, its use in managing posterior scleritis has not been reported. We report the first case of SCS-TA used in the treatment of posterior scleritis. A 67-year-old woman with posterior scleritis complicated by exudative retinal detachment, diagnosed by spectral-domain optical coherence tomography scan (OCT), presented with pain, decreased vision, and redness in the left eye for 8 months. She was previously prescribed topical prednisolone and oral prednisone with minimal improvement. She also had a history of rheumatoid arthritis treated with multiple systemic immunosuppressive agents. After SCS-TA, the patient's pain resolved and visual acuity improved. OCT demonstrated significant reduction in sclerochoroidal thickening. Via its novel delivery method, SCS-TA may be an effective treatment for posterior scleritis. Further studies are needed to establish long-term efficacy and safety of this treatment modality.
眼周曲安奈德（SCS-TA）注射最近被批准用于治疗非感染性葡萄膜炎引起的黄斑水肿。然而，其在治疗后部巩膜炎中的应用尚未见报道。我们报告了首例 SCS-TA 用于治疗后部巩膜炎的病例。一名 67 岁女性，因渗出性视网膜脱离而并发后部巩膜炎，经谱域光相干断层扫描（OCT）诊断，左眼疼痛、视力下降和发红 8 个月。她曾接受过局部泼尼松龙和口服泼尼松龙治疗，但改善不明显。她还患有类风湿性关节炎，曾接受多种全身免疫抑制剂治疗。接受 SCS-TA 治疗后，患者的疼痛得到缓解，视力有所改善。OCT 显示巩膜脉络膜增厚明显减轻。通过其新颖的给药方式，SCS-TA 可能是治疗后部巩膜炎的有效方法。需要进一步的研究来确定这种治疗方式的长期疗效和安全性。
