From the Department of Surgery, Kendall Regional Medical Center.
HCA Miami Burn Center, Miami, FL.
Ann Plast Surg. 2023 Jul 1;91(1):62-63. doi: 10.1097/SAP.0000000000003589.
Pemphigus is a group of autoimmune diseases of the skin and mucous membranes that is characterized by multiple bullae formation. It is caused by autoantibodies directed against the cell surface of keratinocytes, resulting in the loss of cell-cell adhesion of keratinocytes. This disease can be very debilitating and difficult to treat if large surface areas are involved.
We performed a retrospective review of a complex case of pemphigus vulgaris in a 24-year-old man who develop partial-thickness skin lesions distributed throughout the entire body with a total body surface of 80% short after an episode of strep throat treated with amoxicillin.
The patient had a complicated hospital course in which the standard treatment of the disease led to adverse effects that were successfully managed at our busy burn center.
Pemphigus vulgaris is a complex skin disease in which treatment techniques carry their risk and must be tailored to the patient's specific needs. Treatment of this conditions at a burn center would be beneficial as demonstrated with conditions like Stevens-Johnson syndrome and toxic epidermal necrolysis.
天疱疮是一组自身免疫性皮肤和黏膜疾病，其特征是形成多个大疱。它是由针对角朊细胞表面的自身抗体引起的，导致角朊细胞的细胞间黏附丧失。如果涉及大面积的皮肤，这种疾病可能会非常虚弱且难以治疗。
我们对一名 24 岁男性的天疱疮复杂病例进行了回顾性研究，该患者在一次链球菌性咽炎发作后，使用阿莫西林治疗，全身 80%的皮肤出现部分厚度皮损，分布于全身。
该患者的住院过程复杂，标准疾病治疗导致了不良反应，在我们繁忙的烧伤中心得到了成功的处理。
天疱疮是一种复杂的皮肤疾病，其治疗技术存在风险，必须根据患者的具体需求进行调整。在烧伤中心治疗这种疾病是有益的，如史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症。
