Abiotic Stress, Production and Quality Laboratory, Department of Stress Biology and Plant Pathology, CEBAS-CSIC, Murcia, Spain.
J Exp Bot. 2023 Oct 13;74(19):5955-5969. doi: 10.1093/jxb/erad270.
Integration of reactive oxygen species (ROS)-mediated signal transduction pathways via redox sensors and the thiol-dependent signalling network is of increasing interest in cell biology for their implications in plant growth and productivity. Redox regulation is an important point of control in protein structure, interactions, cellular location, and function, with thioredoxins (TRXs) and glutaredoxins (GRXs) being key players in the maintenance of cellular redox homeostasis. The crosstalk between second messengers, ROS, thiol redox signalling, and redox homeostasis-related genes controls almost every aspect of plant development and stress response. We review the emerging roles of TRXs and GRXs in redox-regulated processes interacting with other cell signalling systems such as organellar retrograde communication and gene expression, especially in plants during their development and under stressful environments. This approach will cast light on the specific role of these proteins as redox signalling components, and their importance in different developmental processes during abiotic stress.
活性氧（ROS）介导的信号转导途径通过氧化还原传感器和依赖巯基的信号网络的整合，因其在植物生长和生产力中的意义，在细胞生物学中越来越受到关注。氧化还原调控是蛋白质结构、相互作用、细胞定位和功能的重要控制点，硫氧还蛋白（TRXs）和谷氧还蛋白（GRXs）是维持细胞氧化还原稳态的关键因素。第二信使、ROS、巯基氧化还原信号和与氧化还原稳态相关基因之间的串扰几乎控制着植物发育和应激反应的各个方面。我们综述了 TRXs 和 GRXs 在与其他细胞信号系统（如细胞器逆行通讯和基因表达）相互作用的氧化还原调节过程中的新兴作用，特别是在植物发育和胁迫环境下。这种方法将阐明这些蛋白质作为氧化还原信号成分的特定作用及其在非生物胁迫下不同发育过程中的重要性。
