Pocock N A, Eisman J A, Yeates M G, Sambrook P N, Eberl S
J Clin Invest. 1986 Sep;78(3):618-21. doi: 10.1172/JCI112618.
The relationship between physical fitness and bone mass in the femoral neck, lumbar spine, and forearm was studied in 84 normal women. Femoral neck and lumbar spine bone mineral density and forearm bone mineral content were estimated by absorptiometry. Fitness was quantitated from predicted maximal oxygen uptake. Femoral neck and lumbar bone mineral density were significantly correlated with fitness as well as age and weight. In the 46 postmenopausal subjects, fitness was the only significant predictor of femoral neck bone mineral density, and both weight and fitness predicted the lumbar bone mineral density. These data represent the first demonstration of a correlation between physical fitness, and, by implication, habitual physical activity, and bone mass in the femoral neck; they also support the previous reported correlation between lumbar bone mass and physical activity. The data suggest that increased physical fitness may increase bone mass at the sites of clinically important fractures in osteoporosis.
对84名正常女性的身体健康状况与股骨颈、腰椎和前臂骨量之间的关系进行了研究。通过吸收测定法估算股骨颈和腰椎的骨矿物质密度以及前臂的骨矿物质含量。根据预测的最大摄氧量对身体状况进行量化。股骨颈和腰椎的骨矿物质密度与身体状况以及年龄和体重显著相关。在46名绝经后受试者中，身体状况是股骨颈骨矿物质密度的唯一显著预测指标，体重和身体状况均可预测腰椎骨矿物质密度。这些数据首次证明了身体健康状况（以及由此暗示的习惯性身体活动）与股骨颈骨量之间存在相关性；它们也支持了先前报道的腰椎骨量与身体活动之间的相关性。数据表明，提高身体健康水平可能会增加骨质疏松症中具有临床重要性的骨折部位的骨量。
