Edney D P, Porter J D
J Comp Neurol. 1986 Aug 15;250(3):389-98. doi: 10.1002/cne.902500311.
Brainstem projections of first-order afferent neurons that innervate the suboccipital muscles of the monkey have been determined by using the technique of transganglionic transport of wheat-germ-agglutinin-conjugated horseradish peroxidase (WGA/HRP) and HRP. Neck muscle afferents distribute to several distinct regions located within the caudal brainstem and rostral spinal cord. Terminal labeling was heaviest within the ventral portion of the ipsilateral lateral cuneate nucleus. Muscle afferent terminals also distributed to ventrolateral portions of the pars triangularis division of the cuneate nucleus. Projections were consistent with the known somatotopic (i.e., both place and modality) organization of the cuneate nucleus. Moreover, neck muscle projections to the cuneate nucleus were, in part, coincident with those previously demonstrated for the extraocular muscles (Porter: J. Comp. Neurol. 247:133-143, '86). Sparse terminal projections were noted in the central cervical nucleus. In addition, light terminal labeling was present in group x of the vestibular complex and in an ill-defined region along the lateral margin of the brainstem. Present observations, which provide the first complete description of the central distribution of neck muscle afferent neurons in the primate, may contribute to the known substrate for eye/head coordination.
通过使用小麦胚芽凝集素结合辣根过氧化物酶（WGA/HRP）和HRP的跨神经节运输技术，已确定了支配猴子枕下肌肉的一级传入神经元的脑干投射。颈部肌肉传入神经分布于位于脑干尾部和脊髓前部的几个不同区域。同侧外侧楔束核腹侧部分的终末标记最为密集。肌肉传入终末也分布于楔束核三角部的腹外侧部分。投射与楔束核已知的躯体定位（即位置和模式）组织一致。此外，颈部肌肉向楔束核的投射部分与先前为眼外肌所证实的投射相重合（波特：《比较神经学杂志》247:133 - 143，'86）。在中央颈核中观察到稀疏的终末投射。此外，在前庭复合体的X组以及沿脑干外侧边缘的一个界限不清的区域中存在轻度的终末标记。目前的观察首次完整描述了灵长类动物颈部肌肉传入神经元的中枢分布，可能有助于了解眼/头协调的已知基础。
