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人工主动脉瓣梗阻伴血管翳形成:诊断与处理方法——病例报告

Prosthetic Aortic Valve Obstruction With Pannus Formation, an Approach for Diagnosis and Management: A Case Report.

作者信息

Mousa Aliaa, Arshad Hassaan, Kakhktsyan Tigran, Rashid Muhammad Humayoun, Patel Jigar, Desai Harit

机构信息

Internal Medicine, Capital Health Regional Medical Center, Trenton, USA.

Internal Medicine, Nishtar Medical University, Multan, PAK.

出版信息

Cureus. 2023 Jun 14;15(6):e40416. doi: 10.7759/cureus.40416. eCollection 2023 Jun.

Abstract

Mechanical valve obstructions are critical medical and surgical emergencies that require immediate attention when patients present with new complaints and exhibit signs such as the onset of murmurs or the disappearance of mechanical valve clicks. Obstructions can arise from various causes, including pannus formation, thrombus, vegetations, or subvalvular tissue growth. While pannus formations have been previously reported for the mitral valve, they are less commonly observed in the aortic valve, and several hypotheses have been proposed to understand pannus formation. Accurate diagnosis relies on imaging techniques such as echocardiography and fluoroscopy, and surgical intervention is considered the optimal treatment approach. Here, we present the case of a 69-year-old female who had previously undergone aortic valve replacement and subsequently developed progressive dyspnea, fatigue, and a new onset murmur. Imaging modalities revealed a closed leaflet and a high transvalvular gradient over the valve. The patient underwent a prosthetic redo valve replacement, and post-surgery, she was discharged home without complications.

摘要

机械瓣膜梗阻是严重的医疗和外科急症,当患者出现新的不适症状并表现出如杂音出现或机械瓣膜喀喇音消失等体征时,需要立即引起关注。梗阻可由多种原因引起,包括血管翳形成、血栓、赘生物或瓣下组织生长。虽然此前已有二尖瓣血管翳形成的报道,但在主动脉瓣中较少见,并且已经提出了几种假说来解释血管翳的形成。准确的诊断依赖于超声心动图和荧光透视等成像技术,手术干预被认为是最佳的治疗方法。在此,我们报告一例69岁女性患者,该患者此前接受了主动脉瓣置换术,随后出现进行性呼吸困难、疲劳和新出现的杂音。成像检查显示瓣膜叶关闭及瓣膜上有高跨瓣压差。该患者接受了人工瓣膜再次置换手术,术后无并发症出院回家。

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