Ostrowski Stanisław, Marcinkiewicz Anna, Kośmider Anna, Walczak Andrzej, Zwoliński Radosław, Jaszewski Ryszard
Department of Cardiac Surgery, Medical University of Lodz, Poland.
Kardiochir Torakochirurgia Pol. 2015 Sep;12(3):199-203. doi: 10.5114/kitp.2015.54453. Epub 2015 Sep 28.
Approximately 60 000 prosthetic valves are implanted annually in the USA. The risk of prosthesis dysfunction ranges from 0.1% to 4% per year. Prosthesis valve dysfunction is usually caused by a thrombus obstructing the prosthetic discs. However, 10% of prosthetic valves are dysfunctional due to pannus formation, and 12% of prostheses are damaged by both fibrinous and thrombotic components. The authors present two patients with dysfunctional aortic prostheses who were referred for cardiac surgery. Different surgical solutions were used in the treatment of each case.
CASE STUDY 1: The first patient was a 71-year-old woman whose medical history included arterial hypertension, stable coronary artery disease, diabetes mellitus, chronic obstructive pulmonary disease (COPD), and hypercholesterolemia; she had previously undergone left-sided mastectomy and radiotherapy. The patient was admitted to the Cardiac Surgery Department due to aortic prosthesis dysfunction. Transthoracic echocardiography revealed complete obstruction of one disc and a severe reduction in the mobility of the second. The mean transvalvular gradient was very high. During the operation, pannus covering the discs' surface was found. A biological aortic prosthesis was reimplanted without complications.
CASE STUDY 2: The second patient was an 87-year-old woman with arterial hypertension, persistent atrial fibrillation, and COPD, whose past medical history included gastric ulcer disease and ischemic stroke. As in the case of the first patient, she was admitted due to valvular prosthesis dysfunction. Preoperative transthoracic echocardiography revealed an obstruction of the posterior prosthetic disc and significant aortic regurgitation. Transesophageal echocardiography and fluoroscopy confirmed the prosthetic dysfunction. During the operation, a thrombus growing around a minor pannus was found. The thrombus and pannus were removed, and normal functionality of the prosthetic valve was restored.
Precise and modern diagnostic methods facilitated selection of the treatment method. However, the intraoperative view also seems to be crucial in individualizing the surgical approach.
在美国,每年约有6万个人工心脏瓣膜被植入。人工瓣膜功能障碍的风险为每年0.1%至4%。人工瓣膜功能障碍通常是由血栓阻塞人工瓣膜瓣叶引起的。然而,10%的人工瓣膜因血管翳形成而功能障碍,12%的人工瓣膜同时受到纤维蛋白和血栓成分的损害。作者介绍了两名因主动脉人工瓣膜功能障碍而被转诊至心脏外科的患者。针对每个病例采用了不同的手术解决方案。
病例研究1:第一名患者是一名71岁女性,病史包括动脉高血压、稳定型冠状动脉疾病、糖尿病、慢性阻塞性肺疾病(COPD)和高胆固醇血症;她曾接受过左侧乳房切除术和放疗。该患者因主动脉人工瓣膜功能障碍入住心脏外科。经胸超声心动图显示一个瓣叶完全阻塞,另一个瓣叶活动度严重降低。平均跨瓣压差非常高。手术中发现覆盖瓣叶表面的血管翳。重新植入了一个生物主动脉人工瓣膜,无并发症发生。
病例研究2:第二名患者是一名87岁女性,患有动脉高血压、持续性心房颤动和COPD,既往病史包括胃溃疡病和缺血性中风。与第一名患者一样,她因人工瓣膜功能障碍入院。术前经胸超声心动图显示后人工瓣膜瓣叶阻塞及严重主动脉瓣反流。经食管超声心动图和荧光透视证实了人工瓣膜功能障碍。手术中发现一个围绕小血管翳生长的血栓。清除了血栓和血管翳,恢复了人工瓣膜的正常功能。
精确和现代的诊断方法有助于选择治疗方法。然而,术中视野对于个体化手术方式似乎也至关重要。