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[痛性脂肪增生:关于事实与虚构、临床表现及检查]

[Lipohyperplasia dolorosa : About facts and fiction, clinical presentation and examination].

作者信息

Cornely Manuel E

机构信息

LY.SEARCH, Zentrum für wissenschaftliche Grundlagenforschung lymphologischer Erkrankungen, Biberstr. 7, 50678, Köln, Deutschland.

CG LYMPHA, Köln, Deutschland, Gereonstraße 18-32, 50678.

出版信息

Dermatologie (Heidelb). 2023 Aug;74(8):566-574. doi: 10.1007/s00105-023-05181-y. Epub 2023 Jul 17.

Abstract

Lipohyperplasia dolorosa, also known by the misnomer "lipedema", is a clinical picture first described more than 80 years ago, that in the last 25 years has received increasing attention in medical practices, but also lymphological discussion circles which are otherwise rare in the scientific community. Unfortunately, to put it casually, discussions in social media accelerate the amount of supposed knowledge, an unusual occurrence in the otherwise slow and cautious field of science. Media influences and considerable economic interests resharpen and focus the view, but thus also cloud many women's view of the disease. Combining clinical presentation and a simple clinical examination with a few palpatory findings results in a clear diagnosis that excludes differential diagnoses, in particular obesity. Therapy should only be offered once a precise diagnosis is made. Once the diagnosis is confirmed, it is irreversible and means a lifelong change to the patient's quality of life. Care is, therefore, as always, the first duty of the diagnostician.

摘要

痛性脂肪增生,也被误称为“脂肪性水肿”,是一种80多年前首次被描述的临床症状,在过去25年里,它在医疗实践中受到越来越多的关注,在科学界本就罕见的淋巴学讨论圈子中也是如此。不幸的是,随便说一句,社交媒体上的讨论加速了所谓知识的传播,这在原本缓慢而谨慎的科学领域是不寻常的。媒体影响和巨大的经济利益使观点更加尖锐和集中,但也因此模糊了许多女性对这种疾病的认识。结合临床表现、简单的临床检查以及一些触诊结果可做出明确诊断,排除鉴别诊断,尤其是肥胖症。只有在做出精确诊断后才应提供治疗。一旦确诊,病情就不可逆转,意味着患者的生活质量将发生终身改变。因此,一如既往,谨慎是诊断医生的首要职责。

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