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基于深度强化学习的锥形束CT散射校正自适应散射核反卷积建模

Adaptive scatter kernel deconvolution modeling for cone-beam CT scatter correction via deep reinforcement learning.

作者信息

Piao Zun, Deng Wenxin, Huang Shuang, Lin Guoqin, Qin Peishan, Li Xu, Wu Wangjiang, Qi Mengke, Zhou Linghong, Li Bin, Ma Jianhui, Xu Yuan

机构信息

School of Biomedical Engineering, Southern Medical University, Guangzhou, China.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.

出版信息

Med Phys. 2024 Feb;51(2):1163-1177. doi: 10.1002/mp.16618. Epub 2023 Jul 17.

Abstract

BACKGROUND

Scattering photons can seriously contaminate cone-beam CT (CBCT) image quality with severe artifacts and substantial degradation of CT value accuracy, which is a major concern limiting the widespread application of CBCT in the medical field. The scatter kernel deconvolution (SKD) method commonly used in clinic requires a Monte Carlo (MC) simulation to determine numerous quality-related kernel parameters, and it cannot realize intelligent scatter kernel parameter optimization, causing limited accuracy of scatter estimation.

PURPOSE

Aiming at improving the scatter estimation accuracy of the SKD algorithm, an intelligent scatter correction framework integrating the SKD with deep reinforcement learning (DRL) scheme is proposed.

METHODS

Our method firstly builds a scatter kernel model to iteratively convolve with raw projections, and then the deep Q-network of the DRL scheme is introduced to intelligently interact with the scatter kernel to achieve a projection adaptive parameter optimization. The potential of the proposed framework is demonstrated on CBCT head and pelvis simulation data and experimental CBCT measurement data. Furthermore, we have implemented the U-net based scatter estimation approach for comparison.

RESULTS

The simulation study demonstrates that the mean absolute percentage error (MAPE) of the proposed method is less than 9.72% and the peak signal-to-noise ratio (PSNR) is higher than 23.90 dB, while for the conventional SKD algorithm, the minimum MAPE is 17.92% and the maximum PSNR is 19.32 dB. In the measurement study, we adopt a hardware-based beam stop array algorithm to obtain the scatter-free projections as a comparison baseline, and our method can achieve superior performance with MAPE < 17.79% and PSNR > 16.34 dB.

CONCLUSIONS

In this paper, we propose an intelligent scatter correction framework that integrates the physical scatter kernel model with DRL algorithm, which has the potential to improve the accuracy of the clinical scatter correction method to obtain better CBCT imaging quality.

摘要

背景

散射光子会严重干扰锥束CT(CBCT)图像质量,产生严重伪影并大幅降低CT值准确性,这是限制CBCT在医学领域广泛应用的主要问题。临床常用的散射核反卷积(SKD)方法需要蒙特卡罗(MC)模拟来确定众多与质量相关的核参数,且无法实现智能散射核参数优化,导致散射估计精度有限。

目的

为提高SKD算法的散射估计精度,提出一种将SKD与深度强化学习(DRL)方案相结合的智能散射校正框架。

方法

我们的方法首先构建一个散射核模型与原始投影进行迭代卷积,然后引入DRL方案的深度Q网络与散射核进行智能交互,以实现投影自适应参数优化。在CBCT头部和骨盆模拟数据以及实验CBCT测量数据上验证了所提框架的潜力。此外,我们还实现了基于U-net的散射估计方法进行比较。

结果

模拟研究表明,所提方法的平均绝对百分比误差(MAPE)小于9.72%,峰值信噪比(PSNR)高于23.90dB,而传统SKD算法的最小MAPE为17.92%,最大PSNR为19.32dB。在测量研究中,我们采用基于硬件的束流阻挡阵列算法获取无散射投影作为比较基线,所提方法能实现更优性能,MAPE < 17.79%,PSNR > 16.34dB。

结论

本文提出了一种将物理散射核模型与DRL算法相结合的智能散射校正框架,有潜力提高临床散射校正方法的精度,以获得更好的CBCT成像质量。

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