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创伤后应激障碍共病在接受电休克治疗的重度抑郁症患者中的表现。

Posttraumatic stress disorder comorbidity in patients undergoing ECT for major depressive disorder.

机构信息

Department of Psychiatry and Behavioral Health, The Ohio State University College of Medicine, Columbus, Ohio, USA.

Department of Psychiatry, Duke University, Durham, North Carolina, USA.

出版信息

Ann Clin Psychiatry. 2023 Nov;35(4):223-227. doi: 10.12788/acp.0115.

DOI:10.12788/acp.0115
PMID:37459495
Abstract

BACKGROUND

Posttraumatic stress disorder (PTSD) is not recognized as an indication for electroconvulsive therapy (ECT). However, research indicates promise for this treatment modality. To elucidate the effects of ECT for treating PTSD, prospective research is needed. The first step in assessing the feasibility of such research is to determine if many patients being treated with ECT have comorbid PTSD. This study examined the PTSD comorbidity rates and compared demographic data among patients with major depressive disorder (MDD) who were treated with ECT vs patients with MDD who were not treated with ECT.

METHODS

Data from patients with MDD were obtained from the Nationwide Inpatient Sample.

RESULTS

Approximately 10% of patients undergoing ECT for MDD also had PTSD. The difference in comorbidity of PTSD in those treated with ECT vs those not treated with ECT was approximately 1%.

CONCLUSIONS

Prospective naturalistic studies that examine the response of PTSD to ECT are feasible because a sizable number of patients with PTSD are receiving ECT.

摘要

背景

创伤后应激障碍(PTSD)未被视为电休克疗法(ECT)的适应证。然而,研究表明这种治疗方式有一定的前景。为了阐明ECT 治疗 PTSD 的效果,需要进行前瞻性研究。评估此类研究可行性的第一步是确定接受 ECT 治疗的许多患者是否患有共病 PTSD。本研究调查了 PTSD 的共病率,并比较了接受 ECT 治疗的重度抑郁症(MDD)患者与未接受 ECT 治疗的 MDD 患者的人口统计学数据。

方法

从全国住院患者样本中获取 MDD 患者的数据。

结果

约 10%接受 ECT 治疗 MDD 的患者也患有 PTSD。接受 ECT 治疗与未接受 ECT 治疗的患者 PTSD 共病的差异约为 1%。

结论

因为有相当数量的 PTSD 患者正在接受 ECT 治疗,所以对 PTSD 对 ECT 的反应进行前瞻性自然主义研究是可行的。

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