实验性糖尿病中的延迟脑干听觉诱发电位

Delayed brainstem auditory evoked responses in experimental diabetes mellitus.

作者信息

Buller N, Laurian N, Shvili I, Laurian L

出版信息

J Laryngol Otol. 1986 Aug;100(8):883-91. doi: 10.1017/s0022215100100271.

Abstract

The brainstem auditory evoked responses (BAER) were utilized for the evaluation of central neural transmission in alloxan-induced diabetes in rats. The mean latencies of waves I, III, V and the interpeak latencies III-V and I-V were prolonged in diabetic rats as compared to the same rats before alloxan administration. The incidence of abnormal BAER was more frequent in the group of rats with severe diabetes (82 per cent) than in mildly diabetic animals (42 per cent). Our results may suggest the presence of a central neuropathy in experimental diabetes, which can be detected by the method of BAER.

摘要

利用脑干听觉诱发电位（BAER）评估大鼠四氧嘧啶诱导糖尿病模型的中枢神经传导。与给予四氧嘧啶前相比，糖尿病大鼠I、III、V波的平均潜伏期以及III-V和I-V峰间潜伏期均延长。重度糖尿病大鼠组BAER异常发生率（82%）高于轻度糖尿病动物组（42%）。我们的结果可能提示实验性糖尿病存在中枢神经病变，可通过BAER方法检测到。