Graeber M B, Kreutzberg G W
J Neurocytol. 1986 Jun;15(3):363-73. doi: 10.1007/BF01611438.
Concomitant with the proliferation of satellite microglial cells occurring in the process of motor neuron regeneration, an astrocytic hypertrophy is also seen. A remarkable increase of glial fibrillary acidic protein (GFAP) immunoreactivity is demonstrated in astrocytes of the facial nucleus within a few days following nerve transection. The increase of GFAP antigenicity is associated with an increased appearance of glial filaments and astrocytic processes. We suggest that resident protoplasmic astrocytes become involved in retrograde changes in facial motor neurons and transform into reactive astrocytes. They are of the fibrous type and highly positive for GFAP.
在运动神经元再生过程中伴随卫星小胶质细胞的增殖，还可见星形胶质细胞肥大。在神经横断后几天内，面神经核星形胶质细胞中胶质纤维酸性蛋白（GFAP）免疫反应性显著增加。GFAP抗原性的增加与胶质丝和星形胶质细胞突起的出现增加有关。我们认为，驻留的原浆性星形胶质细胞参与面神经运动神经元的逆行性改变并转化为反应性星形胶质细胞。它们为纤维型，GFAP呈高度阳性。
