Department of Biosciences, Durham University, Durham, DH1 3LE, UK.
J Biol Inorg Chem. 2023 Aug;28(5):451-456. doi: 10.1007/s00775-023-02007-z. Epub 2023 Jul 18.
The control of nutrient availability is an essential ecological function of the host organism in host-microbe systems. Although often overshadowed by macronutrients such as carbohydrates, micronutrient metals are known as key drivers of host-microbe interactions. The ways in which host organisms control nutrient metal availability are dictated by principles in bioinorganic chemistry. Here I ponder about the actions of metal-binding molecules from the host organism in controlling nutrient metal availability to the host microbiota. I hope that these musings will encourage new explorations into the fundamental roles of metals in the ecology of diverse host-microbe systems.
宿主生物体在宿主-微生物系统中控制养分可用性是其基本的生态功能。尽管通常被碳水化合物等大量营养素所掩盖，但微量元素金属被认为是宿主-微生物相互作用的关键驱动因素。宿主生物体控制营养金属可用性的方式取决于生物无机化学的原理。在这里，我思考了宿主生物体中金属结合分子控制宿主微生物组中营养金属可用性的作用。我希望这些思考将鼓励对金属在各种宿主-微生物系统生态中的基本作用进行新的探索。
