维生素 A：肠道中宿主-微生物相互作用的关键协调者。
Vitamin A: a key coordinator of host-microbe interactions in the intestine.
机构信息
Department of Biomedical Science, College of Medicine, Seoul National University, Seoul 03080; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul 03080; Institute of Infectious Diseases, Seoul National University College of Medicine, Seoul 03080, Korea.
出版信息
BMB Rep. 2023 Mar;56(2):133-139. doi: 10.5483/BMBRep.2023-0005.
The human intestine is home to a dense community of microbiota that plays a key role in human health and disease. Nutrients are essential regulators of both host and microbial physiology and function as key coordinators of host-microbe interactions. Therefore, understanding the specific roles and underlying mechanisms of each nutrient in regulating the host-microbe interactions will be essential in developing new strategies for improving human health through microbiota and nutrient intervention. This review will give a basic overview of the role of vitamin A, an essential micronutrient, on human health, and highlight recent findings on the mechanisms by which it regulates the host-microbe interactions. [BMB Reports 2023; 56(3): 133-139].
人类肠道是一个密集的微生物群落的家园，这些微生物在人类健康和疾病中起着关键作用。营养素是宿主和微生物生理功能的重要调节剂，也是宿主-微生物相互作用的关键协调者。因此，了解每种营养素在调节宿主-微生物相互作用中的具体作用和潜在机制，对于通过微生物群和营养干预来改善人类健康的新策略的发展至关重要。本综述将概述必需微量营养素维生素 A 对人类健康的作用，并重点介绍其调节宿主-微生物相互作用的机制的最新发现。[BMB 报告 2023; 56(3): 133-139]。
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