关于心理健康受试者灰质与分裂型人格特质的相关性
On the Correlations of Gray Matter with Schizotypy in Mentally Healthy Subjects.
作者信息
Lebedeva I S, Tomyshev A S, Pechenkova E V
机构信息
Scientific Center of Mental Health, Moscow, Russia.
National Research University Higher School of Economics (HSE University), Moscow, Russia.
出版信息
Bull Exp Biol Med. 2023 Jun;175(2):291-294. doi: 10.1007/s10517-023-05852-9. Epub 2023 Jul 18.
We analyzed the relationships between morphometric characteristics of brain gray matter and schizotypy. Mentally healthy subjects (n=164, age 18-35 years) completed Russian version of SPQ-74 test and underwent high-field 3T MRI. Cortical thickness in the right frontal pole (determined with FreeSurfer 6.0.0) positively correlated with negative schizotypy factor. The revealed features can reflect the protective mechanisms (resilience) against the development of mental disorders and also can be a result of individual ontogenesis trajectories manifested in deceleration of the decrease of the cortex thickness during first 3 decades of life.
我们分析了脑灰质形态计量学特征与精神分裂症型人格之间的关系。心理健康受试者（n = 164，年龄18 - 35岁）完成了俄语版SPQ - 74测试，并接受了高场3T磁共振成像检查。右额极的皮质厚度（使用FreeSurfer 6.0.0测定）与阴性精神分裂症型人格因子呈正相关。所揭示的特征可以反映针对精神障碍发展的保护机制（恢复力），也可能是个体发育轨迹的结果，表现为在生命的前三十年中皮质厚度下降减速。
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