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癌症 RNA 疫苗的文献计量分析。

Bibliometric analysis of RNA vaccines for cancer.

机构信息

Blood Sample Collection, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

Department of Urology, Heilongjiang Provincial Hospital, Harbin Institute of Technology, Harbin, China.

出版信息

Hum Vaccin Immunother. 2023 Aug 1;19(2):2231333. doi: 10.1080/21645515.2023.2231333. Epub 2023 Jul 18.

DOI:10.1080/21645515.2023.2231333
PMID:37464256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10361146/
Abstract

Cancer represents a challenging medical problem worldwide. Several exploratory studies have been conducted to overcome these limitations. RNA vaccines play an important role in cancer prevention and treatment. Recent studies have shown that RNA vaccines play an important role in cancer prevention. However, there are currently no relevant bibliometric studies. This study aimed to apply bibliometrics to summarize the knowledge structure and research hotspots regarding the role of RNA vaccines in cancer. Publications related to RNA vaccines in cancer were searched on the web of science core collection (WoSCC) database. VOSviewers, CiteSpace and R package "bibliometrix" were used to conduct this bibliometric analysis. A total of 1399 articles were included, comprising 803 original articles and 596 reviews. The number of studies on RNA vaccines against cancer has been increasing annually. China and the United States were the principal countries of origin of publications. Johannes Gutenberg University Mainz, NCI, and Duke University were the main organizations. is the leading journal in the field. Hot keywords included tumor antigens, lipid nanoparticles, emerging roles, and dendritic cells. This is the bibliometric study to summarize the research trends and development of RNA vaccines for cancer. This information will provide a reference for researchers studying RNA vaccines against cancer.

摘要

癌症是全球面临的一项严峻医学挑战。为了克服这些局限性，已经开展了多项探索性研究。RNA 疫苗在癌症的预防和治疗中发挥着重要作用。最近的研究表明，RNA 疫苗在癌症预防中发挥着重要作用。然而，目前尚无相关的文献计量学研究。本研究旨在应用文献计量学方法总结 RNA 疫苗在癌症中的作用的知识结构和研究热点。在 Web of Science 核心合集（WoSCC）数据库中检索与癌症中的 RNA 疫苗相关的出版物。使用 VOSviewer、CiteSpace 和 R 包“bibliometrix”进行了这项文献计量分析。共纳入 1399 篇文章，包括 803 篇原始文章和 596 篇综述。针对癌症的 RNA 疫苗研究数量逐年增加。中国和美国是发表论文的主要国家。美因茨约翰内斯古腾堡大学、美国国家癌症研究所和杜克大学是主要的研究机构。Cancer Immunology, Immunotherapy 是该领域的领先期刊。热门关键词包括肿瘤抗原、脂质纳米粒、新兴作用和树突状细胞。这是一项对 RNA 疫苗治疗癌症的研究趋势和发展进行总结的文献计量学研究。这些信息将为研究 RNA 疫苗治疗癌症的研究人员提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/592da032546d/KHVI_A_2231333_F0008_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/07725e3e9fd8/KHVI_A_2231333_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/feb3cc261f6d/KHVI_A_2231333_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/904a34e9b3df/KHVI_A_2231333_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/f1fb2b75a0d7/KHVI_A_2231333_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/6c7faab9957e/KHVI_A_2231333_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/318c0c6a99ef/KHVI_A_2231333_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/cdd4c2cc9696/KHVI_A_2231333_F0007_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/592da032546d/KHVI_A_2231333_F0008_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/07725e3e9fd8/KHVI_A_2231333_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/feb3cc261f6d/KHVI_A_2231333_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/904a34e9b3df/KHVI_A_2231333_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/f1fb2b75a0d7/KHVI_A_2231333_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/6c7faab9957e/KHVI_A_2231333_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/318c0c6a99ef/KHVI_A_2231333_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/cdd4c2cc9696/KHVI_A_2231333_F0007_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643f/10361146/592da032546d/KHVI_A_2231333_F0008_OC.jpg

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引用本文的文献

[1]
Overview of current research on traditional Chinese medicine in skin disease treatment: a bibliometric analysis from 2014 to 2024.

Pharm Biol. 2025-12

[2]
Research hotspots and trends in immunotherapy for cholangiocarcinoma: a bibliometric analysis (2014-2023).

Front Immunol. 2024-11-26

本文引用的文献

[1]
Trends in research related to vaccine and cancer prevention from 1992 to 2022: A 30-years bibliometric analysis.

Hum Vaccin Immunother. 2023-12-31

[2]
Eliciting effective tumor immunity against ovarian cancer by cancer stem cell vaccination.

Biomed Pharmacother. 2023-5

[3]
LRP2 and DOCK8 Are Potential Antigens for mRNA Vaccine Development in Immunologically 'Cold' KIRC Tumours.

Vaccines (Basel). 2023-2-9

[4]
mRNA-From COVID-19 Treatment to Cancer Immunotherapy.

Biomedicines. 2023-1-22

[5]
mRNA Vaccine - A New Cancer Treatment Strategy.

Curr Cancer Drug Targets. 2023

[6]
Polymer-Based mRNA Delivery Strategies for Advanced Therapies.

Adv Healthc Mater. 2023-6

[7]
Therapeutic Vaccination for HPV-Mediated Cancers.

Curr Otorhinolaryngol Rep. 2023

[8]
Targeting intracellular Neu1 for coronavirus infection treatment.

iScience. 2023-2-17

[9]
Cancer statistics, 2023.

CA Cancer J Clin. 2023-1

[10]
VOSviewer and Bibliometrix.

J Med Libr Assoc. 2022-7-1

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