State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing, 210023, China.
Chembiochem. 2023 Sep 1;24(17):e202300420. doi: 10.1002/cbic.202300420. Epub 2023 Aug 1.
Using oligonucleotides to weave 2D tiles such as double crossovers (DX) and multi-arm junction (mAJ) tiles and arrays is well-known, but weaving 3D tiles is rare. Here, we report the construction of two new bilayer tiles in high yield using small circular 84mer oligonucleotides as scaffolds. Further, we designed five E-tiling approaches to construct porous nanotubes of microns long in medium yield via solution assembly and densely covered planar microscale arrays via surface-mediated assembly.
使用寡核苷酸来编织二维的图块，如双链交叉（DX）和多臂连接（mAJ）图块和阵列，这是众所周知的，但编织三维的图块则很少见。在这里，我们报告了使用小的圆形 84 个碱基对的寡核苷酸作为支架，以高产率构建两种新的双层图块。此外，我们设计了五种 E 型图块的组装方法，通过溶液组装构建了微米长的多孔纳米管，通过表面介导组装构建了密集覆盖的平面微尺度阵列。
