Sadeghi Boogar Shahrokh, Sivandzadeh Gholam Reza, Sehatpour Faezeh, Dadashpour Nazanin, Goodarzian MReza, Parvar Seyedeh Yasamin
Gastroentrohepatology Research Center Shiraz University of Medical Sciences Shiraz Iran.
Gastroentrohepatology Research Center, Department of Internal Medicine, School of Medicine Shiraz University of Medical Sciences Shiraz Iran.
Clin Case Rep. 2023 Jul 17;11(7):e7699. doi: 10.1002/ccr3.7699. eCollection 2023 Jul.
In order to early diagnose and prevent the infection dissemination in both suspected solid organ donors and recipients after transplantation, pretransplantation screening tests for rare etiologies like should be necessitated, as they can affect many vital organs, especially the brain, liver, and lungs.
Cryptococcosis is a systemic fungal infection mainly affecting immunocompromised patients. The infection is occasionally seen in 16-21 months after organ transplantation, while early involvement is uncommon within <30 days posttransplantation. In the present study, we reported an unusual case of cryptococcosis infection 21 days after transplantation, limited to the transplanted liver in a 60-year-old male. Treatment with an antifungal agent showed prompt improvement in his clinical condition.
为了早期诊断并预防移植后疑似实体器官供体和受体中的感染传播,应对隐球菌病等罕见病因进行移植前筛查,因为它们可影响多个重要器官,尤其是脑、肝和肺。
隐球菌病是一种主要影响免疫功能低下患者的全身性真菌感染。该感染偶尔在器官移植后16至21个月出现,而在移植后<30天内早期受累并不常见。在本研究中,我们报告了一例移植后21天发生的隐球菌病感染罕见病例,仅局限于一名60岁男性的移植肝脏。抗真菌药物治疗使他的临床状况迅速改善。