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肝移植患者的早期隐球菌病感染:一例报告

Early cryptococcosis infection in a liver transplant patient: A case report.

作者信息

Sadeghi Boogar Shahrokh, Sivandzadeh Gholam Reza, Sehatpour Faezeh, Dadashpour Nazanin, Goodarzian MReza, Parvar Seyedeh Yasamin

机构信息

Gastroentrohepatology Research Center Shiraz University of Medical Sciences Shiraz Iran.

Gastroentrohepatology Research Center, Department of Internal Medicine, School of Medicine Shiraz University of Medical Sciences Shiraz Iran.

出版信息

Clin Case Rep. 2023 Jul 17;11(7):e7699. doi: 10.1002/ccr3.7699. eCollection 2023 Jul.

Abstract

KEY CLINICAL MESSAGE

In order to early diagnose and prevent the infection dissemination in both suspected solid organ donors and recipients after transplantation, pretransplantation screening tests for rare etiologies like should be necessitated, as they can affect many vital organs, especially the brain, liver, and lungs.

ABSTRACT

Cryptococcosis is a systemic fungal infection mainly affecting immunocompromised patients. The infection is occasionally seen in 16-21 months after organ transplantation, while early involvement is uncommon within <30 days posttransplantation. In the present study, we reported an unusual case of cryptococcosis infection 21 days after transplantation, limited to the transplanted liver in a 60-year-old male. Treatment with an antifungal agent showed prompt improvement in his clinical condition.

摘要

关键临床信息

为了早期诊断并预防移植后疑似实体器官供体和受体中的感染传播,应对隐球菌病等罕见病因进行移植前筛查,因为它们可影响多个重要器官,尤其是脑、肝和肺。

摘要

隐球菌病是一种主要影响免疫功能低下患者的全身性真菌感染。该感染偶尔在器官移植后16至21个月出现,而在移植后<30天内早期受累并不常见。在本研究中,我们报告了一例移植后21天发生的隐球菌病感染罕见病例,仅局限于一名60岁男性的移植肝脏。抗真菌药物治疗使他的临床状况迅速改善。

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Early Cardiopulmonary Cryptococcus neoformans Infection After Liver Transplant: A Case Report.肝移植术后早期肺隐球菌感染 1 例报告
Transplant Proc. 2020 Nov;52(9):2790-2794. doi: 10.1016/j.transproceed.2020.06.006. Epub 2020 Jul 5.

引用本文的文献

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Selection for Liver Transplantation: Indications and Evaluation.肝移植的选择:适应证与评估
Curr Hepatol Rep. 2020;19(3):203-212. doi: 10.1007/s11901-020-00527-9. Epub 2020 Jun 19.
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Cryptococcosis today: It is not all about HIV infection.当今的隐球菌病:并非都与艾滋病毒感染有关。
Curr Clin Microbiol Rep. 2017 Jun;4(2):88-95. doi: 10.1007/s40588-017-0064-8. Epub 2017 Apr 17.
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Infections after orthotopic liver transplantation.原位肝移植后的感染
J Clin Exp Hepatol. 2014 Dec;4(4):347-60. doi: 10.1016/j.jceh.2014.07.004. Epub 2014 Jul 24.

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