作为用于治疗哮喘或慢性阻塞性肺疾病的NLRP3抑制剂的稠合双环杂芳基化合物
Fused Bicyclic Heteroaryl Compounds as NLRP3 Inhibitors for Treating Asthma or COPD.
作者信息
Sabnis Ram W
机构信息
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States.
出版信息
ACS Med Chem Lett. 2023 Jun 6;14(7):895-896. doi: 10.1021/acsmedchemlett.3c00236. eCollection 2023 Jul 13.
Abstract
Provided herein are novel fused bicyclic heteroaryl compounds as NLRP3 inhibitors, pharmaceutical compositions, use of such compounds in treating asthma or COPD and processes for preparing such compounds.
摘要
本文提供了作为NLRP3抑制剂的新型稠合双环杂芳基化合物、药物组合物、此类化合物在治疗哮喘或慢性阻塞性肺疾病中的用途以及制备此类化合物的方法。
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