Sabnis Ram W
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States.
ACS Med Chem Lett. 2023 Aug 1;14(8):1047-1048. doi: 10.1021/acsmedchemlett.3c00311. eCollection 2023 Aug 10.
Provided herein are novel pyridazine derivatives as NLRP3 inhibitors, pharmaceutical compositions, use of such compounds in treating asthma, COPD, Parkinson's disease, and Alzheimer's disease, and processes for preparing such compounds.
本文提供了作为NLRP3抑制剂的新型哒嗪衍生物、药物组合物、此类化合物在治疗哮喘、慢性阻塞性肺疾病、帕金森病和阿尔茨海默病中的用途，以及制备此类化合物的方法。
