作为用于治疗阿尔茨海默病和帕金森病的NLRP3抑制剂的新型化合物。
Novel Compounds as NLRP3 Inhibitors for Treating Alzheimer's Disease and Parkinson's Disease.
作者信息
Sabnis Ram W
机构信息
Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States.
出版信息
ACS Med Chem Lett. 2024 Jul 29;15(8):1203-1204. doi: 10.1021/acsmedchemlett.4c00343. eCollection 2024 Aug 8.
Abstract
Provided herein are novel compounds as NLRP3 inhibitors, pharmaceutical compositions, use of such compounds in treating Alzheimer's disease and Parkinson's disease, and processes for preparing such compounds.
摘要
本文提供了作为NLRP3抑制剂的新型化合物、药物组合物、此类化合物在治疗阿尔茨海默病和帕金森病中的用途以及制备此类化合物的方法。
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